Plasmablastic Lymphoma in an Immunocompetent Patient: A Case Report and Literature Review

被引：1

作者：

AlSheef, Mohammed ^{[1
]}

Abuzied, Yacoub ^{[2
]}

Aleid, Bakhitah ^{[3
]}

Shafi, Noura ^{[4
]}

Alshakweer, Wafaa ^{[5
]}

Zaidi, Abdul Rehman Z. ^{[6
]}

机构：

[1] King Fahad Med City, Internal Med & Thrombosis Med Specialties Dept, King, WI USA

[2] King Fahad Med City, Dept Nursing, Rehabil Hosp, King, WI USA

[3] King Fahad Med City, Dept Med Specialties, King, WI USA

[4] King Fahad Med City, Dept Endocrinol, King, WI USA

[5] King Fahad Med City, Dept Histopathol, King, WI USA

[6] Alfaisal Univ, Dept Family & Community Med, Coll Med, Riyadh, Saudi Arabia

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2022年 / 14卷 / 10期

关键词：

lymphoma; aggressive malignancy; b cell neoplasm; immunocompetent; plasmablastic lymphoma; HUMAN-IMMUNODEFICIENCY-VIRUS;

D O I：

10.7759/cureus.30732

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Plasmablastic lymphoma (PBL) is considered an aggressive rare variant of diffuse large B-cell lymphoma that has a predilection to develop in immunocompromised patients, particularly HIV-positive individuals. This report highlights the development of such a rare and aggressive malignancy in a 55-year-old immunocompetent male. It outlines the atypical clinical presentation and pathological features of this disease entity. Overall prognosis and response to chemotherapy differ in the absence or presence of immunosuppression. This report includes a summary of the epidemiologic, clinical, and immunohistochemical characteristics of PBL based on a comprehensive review of the reported cases occurring in immunocompetent individuals.

引用

页数：6

共 13 条

[1] The biology and treatment of plasmablastic lymphoma [J].

Castillo, Jorge J. ;

Bibas, Michele ;

Miranda, Roberto N. .

BLOOD, 2015, 125 (15) :2323-2330

[2] HIV-Negative Plasmablastic Lymphoma: Not in the Mouth [J].

Castillo, Jorge J. ;

Winer, Eric S. ;

Stachurski, Dariusz ;

Perez, Kimberly ;

Jabbour, Melhem ;

Milani, Cannon ;

Colvin, Gerald A. ;

Butera, James N. .

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2011, 11 (02) :185-189

[3] Plasmablastic Lymphoma: A Systematic Review [J].

Castillo, Jorge J. ;

Reagan, John L. .

THESCIENTIFICWORLDJOURNAL, 2011, 11 :687-696

[4] Diffuse large B-cell lymphomas with plasmablastic differentiation represent a heterogeneous group of disease entities [J].

Colomo, L ;

Loong, F ;

Rives, S ;

Pittaluga, S ;

Martínez, A ;

López-Guillermo, A ;

Ojanguren, J ;

Romagosa, V ;

Jaffe, ES ;

Campo, E .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2004, 28 (06) :736-747

[5] Hodgkin Lymphoma, Version 2.2020 [J].

Hoppe, Richard T. ;

Advani, Ranjana H. ;

Ai, Weiyun Z. ;

Ambinder, Richard F. ;

Armand, Philippe ;

Bello, Celeste M. ;

Benitez, Cecil M. ;

Bierman, Philip J. ;

Boughan, Kirsten M. ;

Dabaja, Bouthaina ;

Gordon, Leo, I ;

Hernandez-Ilizaliturri, Francisco J. ;

Herrera, Alex F. ;

Hochberg, Ephraim P. ;

Huang, Jiayi ;

Johnston, Patrick B. ;

Kaminski, Mark S. ;

Kenkre, Vaishalee P. ;

Khan, Nadia ;

Lynch, Ryan C. ;

Maddocks, Kami ;

McConathy, Jonathan ;

McKinney, Matthew ;

Metzger, Monika ;

Morgan, David ;

Mulroney, Carolyn ;

Rabinovitch, Rachel ;

Rosenspire, Karen C. ;

Seropian, Stuart ;

Tao, Randa ;

Winter, Jane N. ;

Yahalom, Joachim ;

Burns, Jennifer L. ;

Ogba, Ndiya .

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2020, 18 (06) :755-781

[6] Classification of lymphoid neoplasms: the microscope as a tool for disease discovery [J].

Jaffe, Elaine S. ;

Harris, Nancy Lee ;

Stein, Harald ;

Isaacson, Peter G. .

BLOOD, 2008, 112 (12) :4384-4399

[7] Human immunodeficiency virus-negative plasmablastic lymphoma in Korea [J].

Kim, Ji Eun ;

Kim, Young A. ;

Kim, Wook Youn ;

Kim, Chul Woo ;

Ko, Young Hye ;

Lee, Geon Kook ;

Choi, Suk-Jin ;

Jeon, Yoon Kyung .

LEUKEMIA & LYMPHOMA, 2009, 50 (04) :582-587

[8] Plasmablastic lymphoma presenting as an arm mass in an individual negative for human immunodeficiency virus: A case report [J].

Kravetz, JD ;

Rose, MG ;

Payne-Blackman, S ;

Federman, DG .

CLINICAL LYMPHOMA & MYELOMA, 2006, 6 (06) :493-495

[9] Epstein-Barr virus and human immunodeficiency virus-negative oral plasmablastic lymphoma [J].

Lee, Ok-Jun ;

Kim, Kyoung-Won ;

Lee, Geon Kook .

JOURNAL OF ORAL PATHOLOGY & MEDICINE, 2006, 35 (06) :382-384

[10] Human immunodeficiency virus-negative plasmablastic lymphoma: A comprehensive analysis of 114 cases [J].

Liu, Min ;

Liu, Bailong ;

Liu, Bin ;

Wang, Qiang ;

Ding, Lijuan ;

Xia, Chengcheng ;

Dong, Lihua .

ONCOLOGY REPORTS, 2015, 33 (04) :1615-1620

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