Association between the site of occurrence and pathological TNM staging in oral squamous cell carcinoma

被引:0
作者
Hannah, R. [1 ]
机构
[1] Saveetha Univ, Saveetha Inst Med & Tech Sci, Saveetha Dent Coll & Hosp, 162 Poonamallee High Rd, Chennai 600077, Tamil Nadu, India
关键词
oral squamous cell carcinoma; TNM staging; buccal mucosa; prognosis; Tongue; CANCER; CLASSIFICATION; MALIGNANCY; SURVIVAL; SOUTH;
D O I
10.6026/973206300161019
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Oral cancer is a worldwide health problem. Risk factors for oral squamous cell carcinoma (OSCC) are tobacco, alcohol, betel nuts, viral infection and dietary habit. The site of occurence of the OSCC differs substantially between different people groups mainly because of variations in the prevalence of risk factors. The prognosis varies based on the site. pTNM is also one of the most useful tools for the prediction of prognosis. Therefore, it is of interest to correlate the pTNM staging with the site of occurrence of the lesion using 36 OSCC cage reports. The results revealed 36.11% of the lesion occurred in buccal mucosa. Stage III pTNM was most prevalent in buccal mucosa and tongue and Stage IV pTNM in the retromolar trigone region by significant association with p value < 0.05. Thus, we report that lesions occurring in the Retromolar region, tongue and buccal mucosa need to be given special attention, as they are associated with early metastasis and poor prognosis. Early diagnosis and appropriate treatment protocol will improve the quality of life for the patients.
引用
收藏
页码:1019 / 1025
页数:7
相关论文
共 38 条
[1]  
Akhter M, 2011, J Oral Maxillofac Pathol, V15, P168, DOI 10.4103/0973-029X.84485
[2]   The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population-based to a more "personalized" approach to cancer staging [J].
Amin, Mahul B. ;
Greene, Frederick L. ;
Edge, Stephen B. ;
Compton, Carolyn C. ;
Gershenwald, Jeffrey E. ;
Brookland, Robert K. ;
Meyer, Laura ;
Gress, Donna M. ;
Byrd, David R. ;
Winchester, David P. .
CA-A CANCER JOURNAL FOR CLINICIANS, 2017, 67 (02) :93-99
[3]  
ANNEROTH G, 1984, SCAND J DENT RES, V92, P448
[4]   NEW MALIGNANCY GRADING IS A BETTER PROGNOSTIC INDICATOR THAN BRODERS GRADING IN ORAL SQUAMOUS-CELL CARCINOMAS [J].
BRYNE, M ;
KOPPANG, HS ;
LILLENG, R ;
STENE, T ;
BANG, G ;
DABELSTEEN, E .
JOURNAL OF ORAL PATHOLOGY & MEDICINE, 1989, 18 (08) :432-437
[5]   Histopathologic parameters in the evaluation of T1 squamous cell carcinomas of the oral cavity [J].
Bundgaard, T ;
Rossen, K ;
Henriksen, SD ;
Charabi, S ;
Sogaard, H ;
Grau, C .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2002, 24 (07) :656-660
[6]  
COSTA AL, 2005, BRAZ J OTORHINOLAR, V71, P181
[7]  
Dib LL, 1994, ACTA ONCOL BRAS, V14, P88
[8]   Trends and clinicopathological characteristics of oral squamous cell carcinomas reported at a tertiary cancer hospital in Nepal during 1999 to 2009 [J].
Gajurel, Rashmi ;
Gautam, Dej Kumar ;
Pun, Chin Bahadur ;
Dhakal, Hari Prasad ;
Petrovski, Beata Eva ;
Costea, Daniela Elena ;
Sapkota, Dipak .
CLINICAL AND EXPERIMENTAL DENTAL RESEARCH, 2020, 6 (03) :356-362
[9]   Syringic acid triggers reactive oxygen species-mediated cytotoxicity in HepG2 cells [J].
Gheena, S. ;
Ezhilarasan, D. .
HUMAN & EXPERIMENTAL TOXICOLOGY, 2019, 38 (06) :694-702
[10]   Heterogeneous Composition Adaptation With Material Convolution Control Features [J].
Gupta, Vikas ;
Tandon, Puneet .
JOURNAL OF COMPUTING AND INFORMATION SCIENCE IN ENGINEERING, 2017, 17 (02)