An "in silico" Bench to Bedside Approach to Investigating Sepsis Biomarkers

被引:0
作者
O'Mahony, Grace [1 ]
Hawthorne, Christopher [1 ]
McQuaid, Karl [1 ]
Lopez-Campos, Guillermo H. [1 ]
机构
[1] Queens Univ Belfast, Wellcome Wolfson Inst Expt Med, Belfast, Antrim, North Ireland
来源
DIGITAL PERSONALIZED HEALTH AND MEDICINE | 2020年 / 270卷
关键词
Biomarkers; Bioinformatics; Sepsis; Natural language processing;
D O I
10.3233/SHTI200359
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Sepsis results in various patient complications and is due to a heightened inflammatory response against infection. This condition requires further exploration of biomarkers. We employed an "in silico" method comprised of text-mining and additionally clinical validation through the Medical Information Mart for Intensive Care. We highlight that Factor VIII shows potential as a pertinent septic shock biomarker..
引用
收藏
页码:1195 / 1196
页数:2
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