An "in silico" Bench to Bedside Approach to Investigating Sepsis Biomarkers

被引：0

作者：

O'Mahony, Grace ^{[1
]}

Hawthorne, Christopher ^{[1
]}

McQuaid, Karl ^{[1
]}

Lopez-Campos, Guillermo H. ^{[1
]}

机构：

[1] Queens Univ Belfast, Wellcome Wolfson Inst Expt Med, Belfast, Antrim, North Ireland

来源：

DIGITAL PERSONALIZED HEALTH AND MEDICINE | 2020年 / 270卷

关键词：

Biomarkers; Bioinformatics; Sepsis; Natural language processing;

D O I：

10.3233/SHTI200359

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Sepsis results in various patient complications and is due to a heightened inflammatory response against infection. This condition requires further exploration of biomarkers. We employed an "in silico" method comprised of text-mining and additionally clinical validation through the Medical Information Mart for Intensive Care. We highlight that Factor VIII shows potential as a pertinent septic shock biomarker..

引用

页码：1195 / 1196

页数：2

共 50 条

[21] Protein Biomarkers for Traumatic and Ischemic Brain Injury: From Bench to Bedside [J].

Zhang, Zhiqun ;

Mondello, Stefania ;

Kobeissy, Firas ;

Rubenstein, Richard ;

Streeter, Jackson ;

Hayes, Ronald L. ;

Wang, Kevin K. W. .

TRANSLATIONAL STROKE RESEARCH, 2011, 2 (04) :455-462

[22] Translational research into frailty from bench to bedside: Salivary biomarkers for inflammaging [J].

Niebla-Cardenas, Alfonssina ;

Bareke, Halin ;

Juanes-Velasco, Pablo ;

Landeira-Vinuela, Alicia ;

Hernandez, Angela-Patricia ;

Montalvillo, Enrique ;

Gongora, Rafael ;

Arroyo-Anllo, Eva ;

Silvia Puente-Gonzalez, Ana ;

Mendez-Sanchez, Roberto ;

Fuentes, Manuel .

EXPERIMENTAL GERONTOLOGY, 2023, 171

[23] Protein Biomarkers for Traumatic and Ischemic Brain Injury: From Bench to Bedside [J].

Zhiqun Zhang ;

Stefania Mondello ;

Firas Kobeissy ;

Richard Rubenstein ;

Jackson Streeter ;

Ronald L. Hayes ;

Kevin K. W. Wang .

Translational Stroke Research, 2011, 2 :455-462

[24] Inflammatory biomarkers and coronary heart disease: from bench to bedside and back [J].

Gina Biasillo ;

Milena Leo ;

Roberta Della Bona ;

Luigi Marzio Biasucci .

Internal and Emergency Medicine, 2010, 5 :225-233

[25] Inflammatory biomarkers and coronary heart disease: from bench to bedside and back [J].

Biasillo, Gina ;

Leo, Milena ;

Della Bona, Roberta ;

Biasucci, Luigi Marzio .

INTERNAL AND EMERGENCY MEDICINE, 2010, 5 (03) :225-233

[26] Antioxidant therapy in sepsis and multi-organ dysfunction: From bench to bedside? [J].

Dorresteijn, M. J. ;

Pickkers, P. .

NETHERLANDS JOURNAL OF CRITICAL CARE, 2008, 12 (06) :254-255

[27] Sepsis-Associated Muscle Wasting: A Comprehensive Review from Bench to Bedside [J].

Yoshihara, Ikumi ;

Kondo, Yutaka ;

Okamoto, Ken ;

Tanaka, Hiroshi .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (05)

[28] Bench to bedside review: therapeutic modulation of nitric oxide in sepsis-an update [J].

Lambden, Simon .

INTENSIVE CARE MEDICINE EXPERIMENTAL, 2019, 7 (01)

[29] From bench to bedside [J].

Verdant, Colin L. .

CRITICAL CARE, 2012, 16 (04)

[30] The role of Procalcitonin in the management of patients with sepsis and respiratory tract infections: from bench to bedside [J].

Papadopoulos, Alexis ;

Bartziokas, Konstantinos ;

Kostikas, Konstantinos .

PNEUMON, 2010, 23 (04) :369-375

← 1 2 3 4 5 →