A versatile synthesis of cyclic diphenyl ether-type diarylheptanoids:: Acerogenins, (±)-galeon, and (±)-pterocarine

被引：30

作者：

Jeong, Byeong-Seon ^{[1
]}

Wang, Qian ^{[1
]}

Son, Jong-Keun ^{[1
]}

Jahng, Yurngdong ^{[1
]}

机构：

[1] Yeungnam Univ, Coll Pharm, Kyongsan 712749, South Korea

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 2007卷 / 08期

关键词：

heptanoids; macrocycles; ethers; aldol reactions; natural products;

D O I：

10.1002/ejoc.200600938

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A versatile method for the total synthesis of cyclic diphenyl ether-type diarylheptanoids, acerogenin C, acerogenin L, (+/-)-galeon, and (+/-)-pterocarine was described. The Ullmann reaction of suitably substituted linear diphenylheptanoids was employed for the intramolecular formation of the key ether intermediates as the final step. The prerequisite diarylheptanoids were prepared by a series of cross-aldol condensation reactions from readily available starting benzaldehydes. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007).

引用

页码：1338 / 1344

页数：7

共 58 条

[1] METAL IONS AND COMPLEXES IN ORGANIC REACTIONS .4. COPPER-PROMOTED PREPARATIONS OF DIARYL ETHERS AND COMPETING HYDROGEN-TRANSFER PROCESSES- [J].