Electrification of transportation systems continues to increase both to reduce the negative effect of petroleum-based transportation on the climate and the quality of life and to allow for enhanced safety and comfort of transportation at large. These developments are often subject to tight constraints on cost, mass, and volume. At the same time, the requirements on the reliability of the systems in these applications are becoming more demanding. Significant literature is available on power electronic systems. Yet, the specifics of the analysis and prevention of failures of different components, subsystems, and systems as they apply in automotive, aerospace, and other transportation systems have, at large still, not yet been fully addressed, and will remain open as the demands of overall cost and performance continuously increase.