Cardio-Oncology An Update on Cardiotoxicity of Cancer-Related Treatment

被引：342

作者：

Lenneman, Carrie G. ^{[1
]}

Sawyer, Douglas B. ^{[2
]}

机构：

[1] Univ Louisville, Sch Med, Dept Med, Louisville, KY 40292 USA

[2] Maine Med Ctr, Cardiovasc Inst, Portland, ME USA

来源：

CIRCULATION RESEARCH | 2016年 / 118卷 / 06期

关键词：

cancer and stroke; cardiac dysfunction; cardiology; cardiotoxicity; oncology; ENDOTHELIAL GROWTH-FACTOR; LONG-TERM SURVIVORS; INDUCED HEART-DISEASE; ANTHRACYCLINE-INDUCED CARDIOTOXICITY; CHEMOTHERAPY-INDUCED CARDIOMYOPATHY; TRASTUZUMAB-RELATED CARDIOTOXICITY; ADVANCED BREAST-CANCER; CARDIOVASCULAR TOXICITY; MOLECULAR-BASIS; LUNG-CANCER;

D O I：

10.1161/CIRCRESAHA.115.303633

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Through the success of basic and disease-specific research, cancer survivors are one of the largest growing subsets of individuals accessing the healthcare system. Interestingly, cardiovascular disease is the second leading cause of morbidity and mortality in cancer survivors after recurrent malignancy. This recognition has helped stimulate a collaboration between oncology and cardiology practitioners and researchers, and the portmanteau cardio-oncology (also known as onco-cardiology) can now be found in many medical centers. This collaboration promises new insights into how cancer therapies impact cardiovascular homeostasis and long-term effects on cancer survivors. In this review, we will discuss the most recent views on the cardiotoxicity related to various classes of chemotherapy agents and radiation. We will also discuss broadly the current strategies for treating and preventing cardiovascular effects of cancer therapy.

引用

页码：1008 / 1020

页数：13

共 143 条

[41] Prone vs Supine Positioning for Breast Cancer Radiotherapy [J].

Formenti, Silvia C. ;

DeWyngaert, J. Keith ;

Jozsef, Gabor ;

Goldberg, Judith D. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2012, 308 (09) :861-863

[42] RADIATION DOSE-VOLUME EFFECTS IN THE HEART [J].

Gagliardi, Giovanna ;

Constine, Louis S. ;

Moiseenko, Vitali ;

Correa, Candace ;

Pierce, Lori J. ;

Allen, Aaron M. ;

Marks, Lawrence B. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 76 (03) :S77-S85

[43] Clinically significant cardiac disease in patients with Hodgkin lymphoma treated with mediastinal irradiation [J].

Galper, Shira L. ;

Yu, James B. ;

Mauch, Peter M. ;

Strasser, Jon F. ;

Silver, Barbara ;

LaCasce, Ann ;

Marcus, Karen J. ;

Stevenson, Mary Ann ;

Chen, Ming Hui ;

Ng, Andrea K. .

BLOOD, 2011, 117 (02) :412-418

[44] Circulating Neuregulin During the Transition From Stage A to Stage B/C Heart Failure in a Breast Cancer Cohort [J].

Geisberg, Carrie A. ;

Abdallah, Wissam M. ;

da Silva, Monica ;

Silverstein, Cheri ;

Smith, Holly M. ;

Abramson, Vandana ;

Mayer, Ingrid ;

Means-Powell, Julie ;

Freehardt, Darla ;

White, Brenda ;

Lenihan, Daniel ;

Sawyer, Douglas B. .

JOURNAL OF CARDIAC FAILURE, 2013, 19 (01) :10-15

[45] Mechanisms of Anthracycline Cardiotoxicity and Strategies to Decrease Cardiac Damage [J].

Geisberg, Carrie Anna ;

Sawyer, Douglas B. .

CURRENT HYPERTENSION REPORTS, 2010, 12 (06) :404-410

[46] Congestive heart failure with vascular endothelial growth factor receptor tyrosine kinase inhibitors [J].

Ghatalia, Pooja ;

Morgan, Charity J. ;

Je, Youjin ;

Nguyen, Paul L. ;

Quoc-Dien Trinh ;

Choueiri, Toni K. ;

Sonpavde, Guru .

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2015, 94 (02) :228-237

[47] Risk of cardiac death after adjuvant radiotherapy for breast cancer [J].

Giordano, SH ;

Kno, YF ;

Freeman, JL ;

Buchholz, TA ;

Hortobagyi, GN ;

Goodwin, JS .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2005, 97 (06) :419-424

[48]

Giordano SH, 2002, CLIN CANCER RES, V8, P3360

[49] Cancer and cardiac mortality among 15-year survivors of cancer diagnosed during childhood or adolescence [J].

Green, DM ;

Hyland, A ;

Chung, CS ;

Zevon, MA ;

Hall, BC .

JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (10) :3207-3215

[50] Abnormal Exercise Response in Long-Term Survivors of Hodgkin Lymphoma Treated With Thoracic Irradiation [J].

Groarke, John D. ;

Tanguturi, Varsha K. ;

Hainer, Jon ;

Klein, Josh ;

Moslehi, Javid J. ;

Ng, Andrea ;

Forman, Daniel E. ;

Di Carli, Marcelo F. ;

Nohria, Anju .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2015, 65 (06) :573-583

← 1 2 3 4 5 6 7 8 9 10 →