Schizophrenia and memory impairment: evidence for a neurocognitive subtype

被引：33

作者：

Vaz, SAM ^{[1
]}

Heinrichs, RW ^{[1
]}

机构：

[1] York Univ, Dept Psychol, N York, ON M3J 1P3, Canada

来源：

PSYCHIATRY RESEARCH | 2002年 / 113卷 / 1-2期

关键词：

schizophrenia; memory; subtypes; positive symptoms; quality of life; medication;

D O I：

10.1016/S0165-1781(02)00246-9

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Evidence is presented that verbal memory impairment distinguishes a subgroup of patients with schizophrenia who also differ in symptom profile and illness adjustment. On the basis of the California Verbal Learning Test (CVLT), a sample of patients was partitioned into memory-impaired (n = 16) and memory-unimpaired groups (n = 16). Groups were matched for age, sex, IQ, and anti-psychotic medication. These groups were then compared using the Brief Psychiatric Rating Scale (BPRS) and the Sickness Impact Profile (SIP). Results indicate that memory-impaired schizophrenia patients experience significantly more positive symptoms and a poorer quality of life than their memory-unimpaired Counterparts. This finding supports the idea that neurocognitive measures are a valuable way of organizing the heterogeneous disease states of schizophrenia. (C) 2002 Elsevier Science Ireland Ltd, All rights reserved.

引用

页码：93 / 105

页数：13

共 99 条

[31] Working memory, attention, and communication disturbances in schizophrenia [J].