Respiratory Health and Urinary Trace Metals among Artisanal Stone-Crushers: A Cross-Sectional Study in Lubumbashi, DR Congo

被引:3
作者
Kayembe-Kitenge, Tony [1 ,2 ,3 ]
Kabange Umba, Irene [1 ]
Musa Obadia, Paul [1 ,2 ,3 ]
Mbuyi-Musanzayi, Sebastien [1 ]
Nkulu Banza, Patient [1 ]
Katoto, Patrick D. M. C. [3 ,4 ,5 ]
Katshiez Nawej, Cyrille [6 ]
Kalenga Ilunga, Georges [1 ,2 ]
Haufroid, Vincent [7 ]
Banza Lubaba Nkulu, Celestin [1 ,2 ]
Nawrot, Tim [3 ]
Nemery, Benoit [3 ]
机构
[1] Univ Lubumbashi, Fac Med, Lubumbashi, DEM REP CONGO
[2] Univ Malemba Nkulu, Fac Med, Dept Internal Med, Malemba, DEM REP CONGO
[3] Katholieke Univ Leuven, Dept Publ Hlth & Primary Care, Ctr Environm & Hlth, B-3000 Leuven, Belgium
[4] Catholic Univ Bukavu, Fac Med, Dept Internal Med, Bukavu, DEM REP CONGO
[5] Catholic Univ Bukavu, Fac Med, Prof Lurhuma Biomed Res Lab, Mycobacterium Unit, Bukavu, DEM REP CONGO
[6] Univ Kolwezi, Fac Med, Dept Internal Med, Kolwezi, DEM REP CONGO
[7] Catholic Univ Louvain, Louvain Ctr Toxicol & Appl Pharmacol, B-1200 Brussels, Belgium
关键词
respiratory health; spirometry; metal biomonitoring; mineral dust; mining; Lubumbashi; FORCED EXPIRATORY VOLUME; LUNG-FUNCTION; PULMONARY-FUNCTION; CRUSHING UNITS; EXPOSURE; SILICA; WORKERS; QUARTZ; PREVALENCE; GUJARAT;
D O I
10.3390/ijerph17249384
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Background: Thousands of artisanal workers are exposed to mineral dusts from various origins in the African Copperbelt. We determined the prevalence of respiratory symptoms, pulmonary function, and urinary metals among artisanal stone-crushers in Lubumbashi. Methods: We conducted a cross-sectional study of 48 male artisanal stone-crushers and 50 male taxi-drivers using a standardized questionnaire and spirometry. Concentrations of trace metals were measured by Inductively Coupled - Plasma Mass Spectrometry (ICP-MS) in urine spot samples. Results: Urinary Co, Ni, As, and Se were higher in stone-crushers than in control participants. Wheezing was more prevalent (p = 0.021) among stone-crushers (23%) than among taxi-drivers (6%). In multiple logistic regression analysis, the job of a stone-crusher was associated to wheezing (adjusted Odds Ratio 4.45, 95% Confidence Interval 1.09-18.24). Stone-crushers had higher values (% predicted) than taxi-drivers for Forced Vital Capacity (105.4 +/- 15.9 vs. 92.2 +/- 17.8, p = 0.048), Forced Expiratory Volume in 1 Second (104.4 +/- 13.7 vs. 88.0 +/- 19.6, p = 0.052), and Maximum Expiratory Flow at 25% of the Forced Vital Capacity (79.0.1 +/- 20.7 vs. 55.7 +/- 30.1, p = 0.078). Conclusion: Stone-crushers were more heavily exposed to mineral dust and various trace elements than taxi-drivers, and they had a fourfold increased risk of reporting wheezing, but they did not have evidence of more respiratory impairment than taxi-drivers.
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页码:1 / 12
页数:12
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