Effects and moderators of exercise on sleep in adults with cancer: Individual patient data and aggregated meta-analyses

被引：24

作者：

Bernard, P. A. ^{[1
,2
,3
,4
,5
]}

Savard, J. ^{[1
,2
,3
]}

Steindorf, K. ^{[6
,7
]}

Sweegers, M. G. ^{[8
]}

Courneya, K. S. ^{[9
]}

Newton, R. U. ^{[10
]}

Aaronson, N. K. ^{[11
]}

Jacobsen, P. B. ^{[12
]}

May, A. M. ^{[13
]}

Galvao, D. A. ^{[10
]}

Chinapaw, M. J. ^{[14
]}

Stuiver, M. M. ^{[15
]}

Griffith, K. A. ^{[16
]}

Mesters, I ^{[17
]}

Knoop, H. ^{[18
]}

Goedendorp, M. M. ^{[19
,20
]}

Bohus, M. ^{[20
,21
]}

Thorsen, L. ^{[22
]}

Schmidt, M. E. ^{[6
,7
]}

Ulrich, C. M. ^{[23
,24
]}

Sonke, G. S. ^{[11
,12
]}

van Harten, W. ^{[11
,23
,24
]}

Winters-Stone, K. M. ^{[25
]}

Velthuis, M. J. ^{[26
]}

Taaffe, D. R. ^{[10
]}

van Mechelen, W. ^{[14
]}

Kersten, M. J. ^{[27
]}

Nollet, F. ^{[28
]}

Wenzel, J. ^{[29
]}

Wiskemann, J. ^{[30
,31
]}

Verdonck-de Leeuw, I. M. ^{[32
,33
]}

Brug, J. ^{[8
,34
]}

Buffart, L. M. ^{[8
,35
]}

机构：

[1] Univ Laval, Canc Res Ctr, Quebec City, PQ, Canada

[2] Univ Laval, Sch Psychol, Quebec City, PQ, Canada

[3] Univ Laval, CHU Quebec, Res Ctr, Quebec City, PQ, Canada

[4] Univ Quebec Montreal, Phys Act Sci Dept, Montreal, PQ, Canada

[5] Univ Inst Mental Hlth Montreal, Res Ctr, Montreal, PQ, Canada

[6] German Canc Res Ctr, Div Phys Act Prevent & Canc, Heidelberg, Germany

[7] Natl Ctr Tumor Dis NCT, Heidelberg, Germany

[8] Vrije Univ Amsterdam, Amsterdam UMC, Dept Epidemiol & Biostat, Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands

[9] Univ Alberta, Fac Phys Educ & Recreat, Edmonton, AB, Canada

[10] Edith Cowan Univ, Exercise Med Res Inst, Joondalup, WA, Australia

[11] Netherlands Canc Inst, Div Psychosocial Res & Epidemiol, Amsterdam, Netherlands

[12] H Lee Moffitt Canc Ctr & Res Inst, Div Populat Sci, Tampa, FL USA

[13] Univ Utrecht, Julius Ctr Hlth Sci & Primary Care, Dept Clin Epidemiol, Univ Med Ctr Utrecht, Utrecht, Netherlands

[14] Vrije Univ Amsterdam, Amsterdam Publ Hlth Res Inst, Dept Publ & Occupat Hlth, Amsterdam UMC, Amsterdam, Netherlands

[15] Netherlands Canc Inst, Dept Physiotherapy, Amsterdam, Netherlands

[16] Univ Maryland, Sch Nursing, Baltimore, MD 21201 USA

[17] Maastricht Univ, Dept Epidemiol, Maastricht, Netherlands

[18] Univ Amsterdam, Dept Med Psychol, Amsterdam UMC, Amsterdam, Netherlands

[19] Univ Groningen, Univ Med Ctr Groningen, Dept Hlth Psychol, Groningen, Netherlands

[20] Heidelberg T Univ, Inst Psychiat & Psychosomat Psychotherapy, Cent Inst Mental Hlth, Mannheim, Germany

[21] Univ Antwerp, Fac Hlth, Antwerp, Belgium

[22] Oslo Univ Hosp, Dept Oncol, Natl Advisory Unit Late Effects Canc, Oslo, Norway

[23] Huntsman Canc Inst, Salt Lake City, UT USA

[24] Univ Utah, Dept Populat Hlth Sci, Salt Lake City, UT USA

[25] Oregon Hlth & Sci Univ, Portland, OR 97201 USA

[26] Netherlands Comprehens Canc Org IKNL, Utrecht, Netherlands

[27] Univ Amsterdam, Dept Hematol, Amsterdam UMC, Amsterdam, Netherlands

[28] Univ Amsterdam, Dept Rehabil Med, Amsterdam Movement Sci, Amsterdam UMC, Amsterdam, Netherlands

[29] Sidney Kimmel Comprehens Canc Ctr, Johns Hopkins Sch Nursing, Johns Hopkins Sch Med, Baltimore, MD USA

[30] Natl Ctr Tumor Dis NCT, Div Med Oncol, Heidelberg, Germany

[31] Heidelberg Univ Hosp, Heidelberg, Germany

[32] Vrije Univ Amsterdam, Dept Otolaryngol Head & Neck Surg, Amsterdam UMC, Amsterdam, Netherlands

[33] Vrije Univ Amsterdam, Dept Clin Psychol, Amsterdam, Netherlands

[34] Natl Inst Publ Hlth & Environm, Bilthoven, Netherlands

[35] Vrije Univ Amsterdam, Canc Ctr Amsterdam, Dept Med Oncol, Amsterdam UMC, Amsterdam, Netherlands

来源：

JOURNAL OF PSYCHOSOMATIC RESEARCH | 2019年 / 124卷

关键词：

Cancer; Physical activity; Treatment; sleep; QUALITY-OF-LIFE; PATIENTS RECEIVING CHEMOTHERAPY; LONG-TERM SURVIVORS; BREAST-CANCER; PHYSICAL-ACTIVITY; ADJUVANT CHEMOTHERAPY; PARTICIPANT DATA; RESISTANCE EXERCISE; AEROBIC EXERCISE; RANDOMIZED-TRIAL;

D O I：

10.1016/j.jpsychores.2019.109746

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Objectives: To evaluate the effects of exercise interventions on sleep disturbances and sleep quality in patients with mixed cancer diagnoses, and identify demographic, clinical, and intervention-related moderators of these effects. Methods: Individual patient data (IPD) and aggregated meta-analyses of randomized controlled trials (RCTs). Using data from the Predicting OptimaL cAncer Rehabilitation and Supportive care project, IPD of 2173 adults (mean age = 54.8) with cancer from 17 RCTs were analyzed. A complementary systematic search was conducted (until November 2018) to study the overall effects and test the representativeness of analyzed IPD. Effect sizes of exercise effects on self-reported sleep outcomes were calculated for all included RCTs. Linear mixed-effect models were used to evaluate the effects of exercise on post-intervention outcome values, adjusting for baseline values. Moderator effects were studied by testing interactions for demographic, clinical and intervention-related characteristics. Results: For all 27 eligible RCTs from the updated search, exercise interventions significantly decreased sleep disturbances in adults with cancer (g = -0.09, 95% CI [-0.16; -0.02]). No significant effect was obtained for sleep quality. RCTs included in IPD analyses constituted a representative sample of the published literature. The intervention effects on sleep disturbances were not significantly moderated by any demographic, clinical, or intervention-related factor, nor by sleep disturbances. Conclusions: This meta-analysis provides some evidence that, compared to control conditions, exercise interventions may improve sleep disturbances, but not sleep quality, in cancer patients, although this effect is of a small magnitude. Among the investigated variables, none was found to significantly moderate the effect of exercise interventions on sleep disturbances.

引用

页数：9

共 72 条

[1] THE EUROPEAN-ORGANIZATION-FOR-RESEARCH-AND-TREATMENT-OF-CANCER QLQ-C30 - A QUALITY-OF-LIFE INSTRUMENT FOR USE IN INTERNATIONAL CLINICAL-TRIALS IN ONCOLOGY
AARONSON, NK
AHMEDZAI, S
BERGMAN, B
BULLINGER, M
CULL, A
DUEZ, NJ
FILIBERTI, A
FLECHTNER, H
FLEISHMAN, SB
DEHAES, JCJM
KAASA, S
KLEE, M
OSOBA, D
RAZAVI, D
ROFE, PB
SCHRAUB, S
SNEEUW, K
SULLIVAN, M
TAKEDA, F
[J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1993, 85 (05) : 365 - 376
[2] [Anonymous], DO SYSTEMATIC REV BA
[3] Joint statement on EPA proposed rule and public availability of data
Berg, Jeremy
Campbell, Philip
Kiermer, Veronique
Raikhel, Natasha
Sweet, Deborah
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (24) : 6098 - 6098
[4] A commentary on the importance of controlling for medication use within trials on the effects of exercise on depression and anxiety
Bernard, P.
Carayol, M.
[J]. MENTAL HEALTH AND PHYSICAL ACTIVITY, 2015, 9 : 10 - 15
[5] Temporal Relationships Between Sleep and Physical Activity Among Breast Cancer Patients With Insomnia
Bernard, Paquito
Ivers, Hans
Savard, Marie-Helene
Savard, Josee
[J]. HEALTH PSYCHOLOGY, 2016, 35 (12) : 1307 - 1315
[6] Agreement between accelerometer-assessed and self-reported physical activity and sedentary time in colon cancer survivors
Boyle, Terry
Lynch, Brigid M.
Courneya, Kerry S.
Vallance, Jeff K.
[J]. SUPPORTIVE CARE IN CANCER, 2015, 23 (04) : 1121 - 1126
[7] A randomized dose-response trial of aerobic exercise and health-related quality of life in colon cancer survivors
Brown, Justin C.
Damjanov, Nevena
Courneya, Kerry S.
Troxel, Andrea B.
Zemel, Babette S.
Rickels, Michael R.
Ky, Bonnie
Rhim, Andrew D.
Rustgi, Anil K.
Schmitz, Kathryn H.
[J]. PSYCHO-ONCOLOGY, 2018, 27 (04) : 1221 - 1228
[8] Targeting Exercise Interventions to Patients With Cancer in Need: An Individual Patient Data Meta-Analysis
Buffart, Laurien M.
Sweegers, Maike G.
May, Anne M.
Chinapaw, Mai J.
van Vulpen, Jonna K.
Newton, Rob U.
Galvao, Daniel A.
Aaronson, Neil K.
Stuiver, Martijn M.
Jacobsen, Paul B.
Verdonck-de Leeuw, Irma M.
Steindorf, Karen
Irwin, Melinda L.
Hayes, Sandi
Griffith, Kathleen A.
Lucia, Alejandro
Herrero-Roman, Fernando
Mesters, Ilse
van Weert, Ellen
Knoop, Hans
Goedendorp, Martine M.
Mutrie, Nanette
Daley, Amanda J.
McConnachie, Alex
Bohus, Martin
Thorsen, Lene
Schulz, Karl-Heinz
Short, Camille E.
James, Erica L.
Plotnikoff, Ronald C.
Arbane, Gill
Schmidt, Martina E.
Potthoff, Karin
van Beurden, Marc
Oldenburg, Hester S.
Sonke, Gabe S.
van Harten, Wim H.
Garrod, Rachel
Schmitz, Kathryn H.
Winters-Stone, Kerri M.
Velthuis, Miranda J.
Taaffe, Dennis R.
van Mechelen, Willem
Kersten, Marie Jose
Nollet, Frans
Wenzel, Jennifer
Wiskemann, Joachim
Brug, Johannes
Courneya, Kerry S.
[J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2018, 110 (11):
[9] Effects and moderators of exercise on quality of life and physical function in patients with cancer: An individual patient data meta-analysis of 34 RCTs
Buffart, Laurien M.
Kalter, Joeri
Sweegers, Maike G.
Courneya, Kerry S.
Newton, Robert U.
Aaronson, Neil K.
Jacobsen, Paul B.
May, Anne M.
Galvao, Daniel A.
Chinapaw, Mai J.
Steindorf, Karen
Irwin, Melinda L.
Stuiver, Martijn M.
Hayes, Sandi
Griffith, Kathleen A.
Lucia, Alejandro
Mesters, Ilse
van Weert, Ellen
Knoop, Hans
Goedendorp, Martine M.
Mutrie, Nanette
Daley, Amanda J.
McConnachie, Alex
Bohus, Martin
Thorsen, Lene
Schulz, Karl-Heinz
Short, Camille E.
James, Erica L.
Plotnikoff, Ron C.
Arbane, Gill
Schmidt, Martina E.
Potthoff, Karin
van Beurden, Marc
Oldenburg, Hester S.
Sonke, Gabe S.
van Harten, Wim H.
Garrod, Rachel
Schmitz, Kathryn H.
Winters-Stone, Kerri M.
Velthuis, Miranda J.
Taaffe, Dennis R.
van Mechelen, Willem
Kersten, Marie Jose
Nollet, Frans
Wenzel, Jennifer
Wiskemann, Joachim
Verdonck-de Leeuw, Irma M.
Brug, Johannes
[J]. CANCER TREATMENT REVIEWS, 2017, 52 : 91 - 104
[10] The Effect, Moderators, and Mediators of Resistance and Aerobic Exercise on Health-Related Quality of Life in Older Long-Term Survivors of Prostate Cancer
Buffart, Laurien M.
Newton, Robert U.
Chinapaw, Mai J.
Taaffe, Dennis R.
Spry, Nigel A.
Denham, James W.
Joseph, David J.
Lamb, David S.
Brug, Johannes
Galvao, Daniel A.
[J]. CANCER, 2015, 121 (16) : 2821 - 2830

← 1 2 3 4 5 6 7 8 →