Microwave-assisted solid-phase synthesis of peptoids

被引：154

作者：

Olivos, HJ

Alluri, PG

Reddy, MM

Salony, D

Kodadek, T

机构：

[1] Univ Texas, SW Med Ctr Dallas, Ctr Biomed Invest, Dept Internal Med, Dallas, TX 75390 USA

[2] Univ Texas, SW Med Ctr Dallas, Ctr Biomed Invest, Dept Mol Biol, Dallas, TX 75390 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 23期

关键词：

D O I：

10.1021/ol0267578

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Microwave irradiation reduces the reaction time for the solid-phase synthesis of peptoids. Under these conditions, coupling of each residue requires only 1 min. The purity and yields of peptoids synthesized in this way are as good as or better than those achieved using standard methods.

引用

收藏

页码：4057 / 4059

页数：3

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