The Beneficial Effects of Mind-Body Exercises for People With Mild Cognitive Impairment: a Systematic Review With Meta-analysis

Objective: To objectively evaluate the most common forms of mind-body exercise (MBE) (tai chi, yoga, qigong) on cognitive function among people with mild cognitive impairment (MCI). Data Sources: We searched 6 electronic databases (Scopus, PubMed, PsycINFO, WanFang, Web of Science, CNKI) from inception until September 2018. Study Selection: Nine randomized controlled trials and 3 nonrandomized controlled trials were included for meta-analysis. Data Extraction: Two researchers independently performed the literature searches, study selection, data extraction, and methodological quality assessment using the revised Physiotherapy Evidence Database (PEDro) scale. Data Synthesis: The pooled effect size (standardized mean difference [SMD]) was calculated while random-effect model was selected. Overall results of the meta-analysis (N = 1298 people with MCI) indicated that MBE significantly improved attention (SMD = 0.39, 95% confidence interval [CI] 0.07-0.71, P = .02, I-2 = 31.6%, n = 245), short-term memory (SMD = 0.74, 95% CI 0.57-0.90, P<.001, I-2 = 0%, n = 861), executive function (SMD = -0.42, 95% CI -0.63 to -0.21, P<.001, I-2 = 38.54%, n = 701), visual-spatial/executive function (SMD = 0.35, 95% CI 0.07-0.64, P<.05, I-2 = 0%, n = 285), and global cognitive function (SMD = 0.36, 95% CI 0.2-0.52, P<.001, I-2 = 15.12%, n = 902). However, the significant positive effect on cognitive processing speed was not observed following MBE interventions (SMD = 0.31, 95% CI -0.01 to 0.63, P =.054, I-2 = 28.66%, n = 233). Conclusions: Study findings of this meta-analysis suggest that MBE have the potential to improve various cognitive functions in people with MCI. (C) 2019 by the American Congress of Rehabilitation Medicine