Differential chronopotentiometric stripping method tor the determination of purines and DNA concentration using an electrochemically pretreated glassy carbon electrode

被引：0

作者：

Jia Wen-Li ^{[1
]}

Li Tian-Hua ^{[1
]}

Zhang Jing-Jing ^{[1
]}

Wang Huai-Sheng ^{[1
]}

机构：

[1] Liaocheng Univ, Coll Chem & Chem Engn, Inst Analyt Chem, Liaocheng 252059, Peoples R China

来源：

CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 2006年 / 27卷 / 11期

关键词：

DNA; purine bases and the corresponding nucleosides; electrochemically pretreated glassy carbon electrode; chronopotentiometric stripping analysis;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The differential chronopotentiometric stripping method was used for the sensitive and selective determination of DNA and purines bases or the nucleosides concentrations in 0.1 mol/L phosphate buffer solution with pH = 4.0 by using an electrochemically pretreated glassy carbon electrode. The results indicate that the electrochemically modified GCE could accumulate purities and ssDNA by effective adsorption and produce sensitive differential stripping peaks. The stripping peak heights(dt/dE) were linear with the concentrations of purine bases and denatured DNA in the suitable range. Some useful information related to DNA damage could be also acquired.

引用

页码：2056 / 2060

页数：5

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