Recent Advances in the Pharmacological Activities of Dioscin

被引：69

作者：

Yang, Longfei ^{[1
]}

Ren, Shengnan ^{[2
]}

Xu, Fei ^{[3
]}

Ma, Zhiming ^{[4
]}

Liu, Xin ^{[5
]}

Wang, Lufei ^{[5
]}

机构：

[1] Jilin Univ, Hosp 2, Jilin Prov Key Lab Mol & Chem Genet, Changchun 130041, Jilin, Peoples R China

[2] Jilin Univ, China Japan Union Hosp, Dept Surg, Changchun 130033, Jilin, Peoples R China

[3] Jilin Univ, Hosp 2, Dept Acupuncture & Moxibust, Changchun 130041, Jilin, Peoples R China

[4] Jilin Univ, Hosp 2, Dept Gastrointestinal Nutr & Hernia Surg, Changchun 130041, Jilin, Peoples R China

[5] Jilin Univ, Hosp 2, Eye Ctr, Changchun 130024, Jilin, Peoples R China

来源：

BIOMED RESEARCH INTERNATIONAL | 2019年 / 2019卷

基金：

中国国家自然科学基金;

关键词：

NATURAL STEROID SAPONIN; DIOSCOREA-PANTHAICA PRAIN; PARIS-CHINENSIS DIOSCIN; OVARIAN-CANCER CELLS; DOWN-REGULATING MDR1; ACUTE LIVER-INJURY; OXIDATIVE STRESS; IN-VITRO; ISCHEMIA/REPERFUSION INJURY; SIGNALING PATHWAY;

D O I：

10.1155/2019/5763602

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Dioscin is a typical saponin with multiple pharmacological activities. The past few years have seen an emerging interest in and growing research on this pleiotropic saponin. Here, we review the emerging pharmacological activities reported recently, with foci on its antitumor, antimicrobial, anti-inflammatory, antioxidative, and tissue-protective properties. The potential use of dioscin in therapies of diverse clinical disorders is also discussed.

引用

页数：13

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