Green synthesis of a temperature sensitive hydrogel

被引：44

作者：

Temtem, Marcio ^{[1
]}

Casimiro, Teresa

Mano, Joao F.

Aguiar-Ricardo, Ana

机构：

[1] Univ Nova Lisboa, Fac Ciencias & Tecnol, Dept Quim, REQUIMTE CQFB, P-2829516 Caparica, Portugal

[2] Univ Minho, 3Bs Res Grp, P-4710057 Braga, Portugal

[3] Univ Minho, Dept Polymer Engn, P-4810058 Guimaraes, Portugal

来源：

GREEN CHEMISTRY | 2007年 / 9卷 / 01期

关键词：

D O I：

10.1039/b603930h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A thermoresponsive hydrogel, poly(N-isopropylacrylamide), PNIPAAm, with possible applications in drug delivery, tissue engineering and as smart membranes with tuned permeability, was synthesised in supercritical carbon dioxide. A strategy of solvent-free impregnation/coating of polymeric surfaces with PNIPAAm is also suggested, in order to further extend the applications of membranes or porous bulky systems. In this work, in situ synthesis of PNIPAAm within a chitosan scaffold was tested as a proof of concept, in order to produce smart partially-biodegradable scaffolds for tissue engineering applications.

引用

页码：75 / 79

页数：5

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