Trichiliton A, a Novel Limonoid from Trichilia connaroides

被引：29
作者：
Fang, Xin [1 ,2 ]
Di, Yingtong [1 ]
Geng, Zhaoliang [1 ]
Tan, Chenjian [1 ]
Guo, Jie [3 ]
Ning, Jing [1 ]
Hao, Xiaojiang [1 ]
机构：
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
[3] Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Peoples R China
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 2010卷 / 07期
基金：
美国国家科学基金会;
关键词：
Terpenoids; Natural products; Structure elucidation; Biosynthesis; Reaction mechanisms; SWIETENIA-MACROPHYLLA; NATURAL-PRODUCTS; CARBON SKELETON; RING-SYSTEM; TETRANORTRITERPENOIDS; KHAYANOLIDES; STEREOCHEMISTRY; ANTIFEEDANTS; EXTRACTIVES; INHIBITOR;
D O I：
10.1002/ejoc.200901245
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Trichiliton A (1), a novel limonoid with an unprecedented bicyclo[5.2.1(4,10)]decane motif in the tetranortriterpenoid core, has been isolated from the leaves of Trichilia connaroides. Its structure and absolute configuration have been elucidated by spectroscopic analysis and computational methods. The biosynthetic pathway of compound 1 is discussed and involves an alternative new routine from mexicanolide to phragmalin.
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收藏
页码：1381 / 1387
页数：7
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