APPLICATION ANALYSIS OF 3.0T MRI COMBINED WITH LOW-CONCENTRATION CONTRAST AGENTS AND LOW-DOSE CT PERFUSION IMAGING IN ACUTE ISCHEMIC STROKE

Introduction: The purpose of the study was to investigate the application value of 3.0T MRI combined with low-concentration contrast agents and low-dose CT perfusion imaging in acute ischemic stroke. Methods: A total of 78 patients with acute ischemic stroke who were admitted to our hospital to receive magnetic resonance angiography and perfusion imaging from January 2017 to January 2019 were selected, and their clinical data were retrospectively reviewed. All the patients were divided into control group (n=39) and experimental group (n=39), according to the random number table method. Among them, the control group patients received the contrast agents with the concentration of 0.5 mmol/ml, while the patients in the experimental group the contrast agents with the concentration of 0.25 mmol/ml. Then, relevant indexes such as image quality, signal differences and arterial conditions were compared between the two groups. Results: With taking DSA diagnostic results as the gold standard, there were no statistical differences in the diagnostic accuracy rate of CE-MRI between the two groups; there were no statistical differences in the results of ischemic penumbra and image quality scores between the two groups (P > 0.05); there were significant differences in SNR and CNR at the beginning parts of middle cerebral artery between the two groups (P < 0.05), and there were no statistical significance in other blood flow signals. Conclusion: In the premise of maintaining image quality, the application of 3.0T MRI combined with low-concentration contrast agents and low-dose CT perfusion imaging can reduce the damage caused by high-concentration contrast agents in patients and obviously increase the safety of diagnosis, with high clinical application value in the treatment of acute ischemic stroke, which is worthy of application and promotion.