Murine fetal thymic organ culture (FTOC) demonstrates involvement of apoptosis in the manifestation of adenosine deaminase (ADA) deficiency.

被引:0
|
作者
Van de Wiele, CJ
Hooker, SW
Laurent, AB
Vaughn, JG
Blackburn, MR
Kellems, RE
Yoshida, H
Mak, TW
Thompson, LF
机构
[1] Oklahoma Med Res Fdn, Oklahoma City, OK 73104 USA
[2] Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK 73104 USA
[3] Univ Texas, Houston, TX 77030 USA
[4] Amgen Inst, Toronto, ON M5G 2C1, Canada
来源
FASEB JOURNAL | 2000年 / 14卷 / 06期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:A919 / A919
页数:1
相关论文
共 8 条
  • [1] Adenosine kinase (AK) inhibition rescues T cell development in a murine fetal thymic organ culture (FTOC) model of adenosine deaminase (ADA) deficiency.
    Van De Wiele, CJ
    Blackburn, MR
    Kellems, RE
    Thompson, LF
    FASEB JOURNAL, 2001, 15 (05): : A1015 - A1015
  • [2] 2'-deoxycoformycin blocks T cell differentiation in murine fetal thymic organ culture: A model for adenosine deaminase deficiency.
    Resta, R
    Jiang, H
    Hooker, SW
    Laurent, AB
    Knudsen, TB
    THompson, LF
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1997, 99 (01) : 1603 - 1603
  • [3] Insights into adenosine deaminase deficiency provided by murine fetal thymic organ culture with 2′-deoxycoformycin
    Resta, R
    Jiang, H
    Hooker, SW
    Laurent, AB
    Thompson, LF
    PURINE AND PYRIMIDINE METABOLISM IN MAN IX, 1998, 431 : 451 - 454
  • [4] Loss of adenosine deaminase activity inhibits beta selection in murine fetal thymic organ culture
    Thompson, LF
    Hooker, SW
    Laurent, AB
    Daniels, S
    Hershfield, MS
    Resta, R
    FASEB JOURNAL, 1998, 12 (05): : A924 - A924
  • [5] Further differentiation of murine double-positive thymocytes is inhibited in adenosine deaminase-deficient murine fetal thymic organ culture
    Van De Wiele, C. Justin
    Joachims, Michelle L.
    Fesler, Amy M.
    Vaughn, James G.
    Blackburn, Michael R.
    McGee, Stephanie T.
    Thompson, Linda F.
    JOURNAL OF IMMUNOLOGY, 2006, 176 (10): : 5925 - 5933
  • [6] Mechanisms of apoptosis in developing thymocytes as revealed by adenosine deaminase-deficient fetal thymic organ cultures
    Thompson, LF
    Vaughn, JG
    Laurent, AB
    Blackburn, MR
    Van De Wiele, CJ
    BIOCHEMICAL PHARMACOLOGY, 2003, 66 (08) : 1595 - 1599
  • [7] T lymphoid precursors in CD34(+) cells from human cord blood and adult marrow identified in murine fetal thymic organ culture (FTOC) system
    Robin, C
    Pflumio, F
    Vainchenker, W
    Coulombel, L
    Rouches, A
    Ardouin, P
    BRITISH JOURNAL OF HAEMATOLOGY, 1996, 93 : 804 - 804
  • [8] T lymphoid precursors in CD34(+) cells from human cord blood and adult marrow identified in murine fetal thymic organ culture (FTOC) system
    Robin, C
    Pflumio, F
    Vainchenker, W
    Coulombel, L
    BRITISH JOURNAL OF HAEMATOLOGY, 1996, 93 : 804 - 804