Primary synovial sarcoma

Purpose: To describe the clinicopathologic and immunohistochemical features and treatment of a rare case of primary synovial sarcoma of the orbit. Design: Retrospective interventional case report. Participant: A 14-year-old young man with histologically proven synovial sarcoma of the orbit. The diagnosis was confirmed by demonstration of a specific chromosomal translocation by polymerase chain reaction studies. Methods: The patient was treated with orbital exenteration and followed up for 18 months at regular intervals. Results: The tumor was excised completely, and the patient has done well during the initial 1-year follow-up with no sign of recurrence. Conclusions: We report the fourth case of synovial sarcoma of the orbit and, at 14 years of age, the youngest patient reported. (c) 2006 by the American Academy of Ophthalmology.