Discovering orphans' sweet secret: NR4A receptors and hepatic glucose production

被引:12
作者
Diaz, Mauricio Berriel [1 ]
Lemke, Ulrike [1 ]
Herzig, Stephan [1 ]
机构
[1] German Canc Res Ctr, Emmy Noether Res Grp, Mol Metab Control A170, D-69120 Heidelberg, Germany
关键词
D O I
10.1016/j.cmet.2006.10.005
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Aberrant hepatic gluconeogenesis contributes importantly to hyperglycemia in type II diabetic patients. A study by Pei et al. (2006b) identifies NR4A orphan nuclear receptors as a novel branch of cAMP-dependent regulators of hepatic glucose production under healthy and diabetic conditions.
引用
收藏
页码:339 / 340
页数:2
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