Inhibitory effects of human seminal plasma on an ELISA used to detect anti-sperm antibodies: Implications for the determination of sperm quality

被引：7

作者：

Lu, NQ ^{[1
]}

Zha, SW ^{[1
]}

机构：

[1] Jiangsu Family Planning Res Inst, Nanjing 210029, Peoples R China

来源：

JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 2000年 / 47卷 / 01期

关键词：

human seminal plasma; inhibition; anti-sperm antibody; ELISA; sperm quality;

D O I：

10.1016/S0165-0378(00)00051-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The in vitro inhibitory effect of human seminal plasma on an ELISA used to detect anti-sperm antibodies have been observed. The mean inhibition rate of seminal plasma samples from 75 men was 61.5 +/- 23.1%. The inhibition rate of 29 samples from normal sperm group was 71.14 +/- 18.25%, while that of 46 samples from the abnormal sperm group was 55.43 +/- 23.98%. The results show that human seminal plasma from semen with high quality sperms possesses a high inhibitory rate to anti-sperm antibody reactions, suggesting its efficiency for immunosuppression of humoral immune reactions. Its possible implications are discussed. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：33 / 40

页数：8