Panton-Valentine leukocidin-positive Staphylococcus aureus skin and soft tissue infections among children in an emergency department in Madrid, Spain

被引：43
作者：
Daskalaki, M. [1 ]
Rojo, P. [2 ]
Marin-Ferrer, M. [2 ]
Barrios, M. [2 ]
Otero, J. R. [1 ]
Chaves, F. [1 ]
机构：
[1] Hosp Univ 12 Octubre, Microbiol Serv, Madrid, Spain
[2] Hosp Univ 12 Octubre, Serv Pediat, Madrid, Spain
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2010年 / 16卷 / 01期
关键词：
Community-associated infections; emergency department; methicillin resistance; paediatric infections; Panton-Valentine leukocidin; Spain; Staphylococcus aureus; MULTIPLEX PCR STRATEGY; METHICILLIN-RESISTANT; MEC ELEMENT; IDENTIFICATION; PNEUMONIA; DISEASE;
D O I：
10.1111/j.1469-0691.2009.02830.x
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Fifty-three children who attended the emergency department with community-associated (CA) Staphylococcus aureus skin and soft tissue infections (SSTIs) were enrolled in the study. Seven cases of infection (13.2%) were due to methicillin-resistant S. aureus (MRSA). Twelve of 46 available isolates (26.1%) were Panton-Valentine leukocidin (PVL)-positive. PVL-positive S. aureus SSTIs were more frequently associated with abscesses and cellulitis (75% vs. 38%, p 0.028), and more commonly required incision and drainage (75% vs. 21%, p 0.001). Most PVL-positive CA-MRSA isolates belonged to a single multilocus sequence type (ST8). In contrast, PVL-positive methicillin-susceptible S. aureus isolates belonged to four different sequence types (ST8, ST30, ST80, ST120).
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收藏
页码：74 / 77
页数：4
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