Seasonal dynamics and microgeographical spatial heterogeneity of malaria along the China-Myanmar border

被引：27

作者：

Hu, Yue ^{[1
,2
]}

Zhou, Guofa ^{[3
]}

Ruan, Yonghua ^{[2
]}

Lee, Ming-chieh ^{[3
]}

Xu, Xin ^{[1
]}

Deng, Shuang ^{[2
]}

Bai, Yao ^{[1
]}

Zhang, Jie ^{[1
]}

Morris, James ^{[4
]}

Liu, Huaie ^{[1
]}

Wang, Ying ^{[5
]}

Fan, Qi ^{[6
]}

Li, Peipei ^{[6
]}

Wu, Yanrui ^{[1
]}

Yang, Zhaoqing ^{[1
]}

Yan, Guiyun ^{[3
]}

Cui, Liwang ^{[7
]}

机构：

[1] Kunming Med Univ, Dept Pathogen Biol & Immunol, Kunming, Peoples R China

[2] Kunming Med Univ, Dept Pathol, Kunming, Peoples R China

[3] Univ Calif Irvine, Program Publ Hlth, Irvine, CA USA

[4] Clemson Univ, Dept Biochem & Genet, Eukaryot Pathogens Innovat Ctr, Clemson, SC 29631 USA

[5] Third Mil Med Univ, Inst Trop Med, Chongqing, Peoples R China

[6] Dalian Inst Biotechnol, Dalian, Liaoning, Peoples R China

[7] Penn State Univ, Dept Entomol, University Pk, PA 16802 USA

来源：

ACTA TROPICA | 2016年 / 157卷

基金：

美国国家卫生研究院; 中国国家自然科学基金;

关键词：

Clinical malaria; Seasonality; Hotspot; China-Myanmar border; PLASMODIUM-VIVAX; SPATIOTEMPORAL DISTRIBUTION; FALCIPARUM-MALARIA; YUNNAN PROVINCE; RISK-FACTORS; HOT-SPOTS; ELIMINATION; EPIDEMIOLOGY; TRANSMISSION; POPULATION;

D O I：

10.1016/j.actatropica.2016.01.022

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Malaria transmission is heterogeneous in the Greater Mekong Subregion with most of the cases occurring along international borders. Knowledge of transmission hotspots is essential for targeted malaria control and elimination in this region. This study aimed to determine the dynamics of malaria transmission and possible existence of transmission hotspots on a microgeographical scale along the China-Myanmar border. Microscopically confirmed clinical malaria cases were recorded in five border villages through a recently established surveillance system between January 2011 and December 2014. A total of 424 clinical cases with confirmed spatial and temporal information were analyzed, of which 330 (77.8%) were Plasmodium vivax and 88 (20.8%) were Plasmodium falciparum, respectively. The P. vivax and P. falciparum case ratio increased dramatically from 2.2 in 2011 to 4.7 in 2014, demonstrating that P. vivax malaria has become the predominant parasite species. Clinical infections showed a strong bimodal seasonality. There were significant differences in monthly average incidence rates among the study villages with rates in a village in China being 3-8 folds lower than those in nearby villages in Myanmar. Spatial analysis revealed the presence of clinical malaria hotspots in four villages. This information on malaria seasonal dynamics and transmission hotspots should be harnessed for planning targeted control. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：12 / 19

页数：8

共 50 条

[31] Co-infections with Babesia microti and Plasmodium parasites along the China-Myanmar border [J].

Zhou, Xia ;

Li, Sheng-Guo ;

Chen, Shen-Bo ;

Wang, Jia-Zhi ;

Xu, Bin ;

Zhou, He-Jun ;

Ge, Hong-Xiang Zhu ;

Chen, Jun-Hu ;

Hu, Wei .

INFECTIOUS DISEASES OF POVERTY, 2013, 2 :1-7

[32] Co-infections with Babesia microti and Plasmodium parasites along the China-Myanmar border [J].

Xia Zhou ;

Sheng-Guo Li ;

Shen-Bo Chen ;

Jia-Zhi Wang ;

Bin Xu ;

He-Jun Zhou ;

Hong-Xiang Zhu Ge ;

Jun-Hu Chen ;

Wei Hu .

Infectious Diseases of Poverty, 2

[33] No evidence of amplifiedPlasmodium falciparum plasmepsin IIgene copy number in an area with artemisinin-resistant malaria along the China-Myanmar border [J].

Huang, Fang ;

Shrestha, Biraj ;

Liu, Hui ;

Tang, Lin-Hua ;

Zhou, Shui-Sen ;

Zhou, Xiao-Nong ;

Takala-Harrison, Shannon ;

Ringwald, Pascal ;

Nyunt, Myaing M. ;

Plowe, Christopher V. .

MALARIA JOURNAL, 2020, 19 (01)

[34] Investigation and control of a Plasmodium falciparum malaria outbreak in Shan Special Region II of Myanmar along the China-Myanmar Border from June to December 2014 [J].

Liu, Hui ;

Xu, Jian-Wei ;

Yang, Heng-Lin ;

Li, Mei ;

Sun, Cheng-De ;

Yin, Yi-Jie ;

Zheng, Zhi-Liang ;

Zhang, Guang-Yun ;

Yu, Ai-Shui ;

Yang, Yong-Hui ;

Li, Chun-Hui ;

Ai, Shui .

INFECTIOUS DISEASES OF POVERTY, 2016, 5

[35] Shifting from control to elimination: analysis of malaria epidemiological characteristics in Tengchong County around China-Myanmar border, 2005-2014 [J].

Shengguo Li ;

Shouqin Yin ;

Jiazhi Wang ;

Xishang Li ;

Jun Feng .

Malaria Journal, 15

[36] Surveillance of Plasmodium vivax transmission using serological models in the border areas of China-Myanmar [J].

Yao, Meixue ;

Xiao, Lishun ;

Sun, Xiaodong ;

Lin, Zurui ;

Hao, Xiao ;

Bai, Qiong-qiong ;

Yin, De-Hui .

MALARIA JOURNAL, 2022, 21 (01)

[37] Plasmodium malariae and Plasmodium ovale infections in the China-Myanmar border area [J].

Li, Peipei ;

Zhao, Zhenjun ;

Xing, Hua ;

Li, Wenli ;

Zhu, Xiaotong ;

Cao, Yaming ;

Yang, Zhaoqing ;

Sattabongkot, Jetsumon ;

Yan, Guiyun ;

Fan, Qi ;

Cui, Liwang .

MALARIA JOURNAL, 2016, 15 :1-10

[38] Monitoring Plasmodium vivax chloroquine sensitivity along China-Myanmar border of Yunnan Province, China during 2008-2013 [J].

Liu, Hui ;

Yang, Heng-lin ;

Tang, Lin-hua ;

Li, Xing-liang ;

Huang, Fang ;

Wang, Jia-zhi ;

Li, Chun-fu ;

Wang, Heng-ye ;

Nie, Ren-hua ;

Guo, Xiang-rui ;

Lin, Ying-xue ;

Li, Mei ;

Xu, Jian-Wei .

MALARIA JOURNAL, 2014, 13

[39] Risk factors associated with slide positivity among febrile patients in a conflict zone of north-eastern Myanmar along the China-Myanmar border [J].

Li, Nana ;

Parker, Daniel M. ;

Yang, Zhaoqing ;

Fan, Qi ;

Zhou, Guofa ;

Ai, Guoping ;

Duan, Jianhua ;

Lee, Ming-Chieh ;

Yan, Guiyun ;

Matthews, Stephen A. ;

Cui, Liwang ;

Wang, Ying .

MALARIA JOURNAL, 2013, 12

[40] Epidemiological and clinical characteristics of the largest COVID-19 outbreak along the China-Myanmar border in Ruili City, Yunnan Province, China [J].

Yan, Xiangyu ;

Hao, Linhui ;

Wang, Zekun ;

Wang, Xuechun ;

Zhang, Xiangyu ;

Li, Tao ;

Jia, Zhongwei ;

Chang, Litao ;

Zhang, Bo ;

Shui, Tiejun .

FRONTIERS IN PUBLIC HEALTH, 2022, 10

← 1 2 3 4 5 →