Total Synthesis of TK-57-164A, Isariotin F, and Their Putative Progenitor Isariotin E

被引:28
作者
Cha, Jacob Y. [1 ]
Huang, Yaodong [1 ]
Pettus, Thomas R. R. [1 ]
机构
[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA
关键词
biomimetic synthesis; cyclization; dearomatization; resorcinol; total synthesis; NEUTRAL SPHINGOMYELINASE; AMINO-ACIDS; DERIVATIVES; INHIBITOR; AZASPIROCYCLIZATION; (+)-SCYPHOSTATIN; GYMNASTATINS; SCYPHOSTATIN; ANTIBIOTICS; METABOLITES;
D O I
10.1002/anie.200904716
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[Chemical equation presented] © 2009 Wiley-VCH Verlag GmbH &. Co. KGaA.
引用
收藏
页码:9519 / 9521
页数:3
相关论文
共 30 条
[11]  
Inoue M., 2004, Angew. Chem. Int. Ed, V116, P4303
[12]   Cyclohexadienone ketals and quinols: Four building blocks potentially useful for enantioselective synthesis [J].
Magdziak, D ;
Meek, SJ ;
Pettus, TRR .
CHEMICAL REVIEWS, 2004, 104 (03) :1383-1429
[13]   Naturally occurring cyclohexane epoxides: Sources, biological activities, and synthesis [J].
Marco-Contelles, J ;
Molina, MT ;
Anjum, S .
CHEMICAL REVIEWS, 2004, 104 (06) :2857-2899
[14]   Total synthesis of (+)-rishirilide B: Development and application of general processes for enantioselective oxidative dearomatization of resorcinol derivatives [J].
Mejorado, Lupe H. ;
Pettus, Thomas R. R. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (49) :15625-15631
[15]   A synthetic study on gymnastatins F and Q: the tandem Michael and aldol reaction approach [J].
Murayama, Kyoko ;
Tanabe, Takamasa ;
Ishikawa, Yuichi ;
Nakamura, Kensuke ;
Nishiyama, Shigeru .
TETRAHEDRON LETTERS, 2009, 50 (26) :3191-3194
[16]  
Nakagawa A, 2004, J. P. Patent, Patent No. [2004074269, WO-A1-2004/074269]
[17]   Synthesis of (±)-epoxysorbicillinol using a novel cyclohexa-2,5-dienone with synthetic applications to other sorbicillin derivatives [J].
Pettus, LH ;
Van de Water, RW ;
Pettus, TRR .
ORGANIC LETTERS, 2001, 3 (06) :905-908
[18]   Diastereoselective spiroannulation of phenolic substrates:: Advances towards the asymmetric formation of the ManumycinM-C7N core skeleton [J].
Plourde, Guy L. ;
Spaetzel, Randy R. ;
Kwasnitza, Jolene S. ;
Scully, Thomas W. .
MOLECULES, 2007, 12 (09) :2215-2222
[19]  
SCHMIDT U, 1983, TETRAHEDRON LETT, V24, P3573
[20]   AMINO-ACIDS AND PEPTIDES .43. DEHYDROAMINO ACIDS .18. SYNTHESIS OF DEHYDROAMINO ACIDS AND AMINO-ACIDS FROM N-ACYL-2-(DIALKYLOXYPHOSPHINYL)-GLYCIN ESTERS .2. [J].
SCHMIDT, U ;
LIEBERKNECHT, A ;
WILD, J .
SYNTHESIS-STUTTGART, 1984, (01) :53-60