Utilizing Paper-Based Devices for Antimicrobial-Resistant Bacteria Detection

被引：119

作者：

Boehle, Katherine E. ^{[1
]}

Gilliand, Jake ^{[2
]}

Wheeldon, Christopher R. ^{[1
]}

Holder, Amethyst ^{[2
]}

Adkins, Jaclyn A. ^{[1
]}

Geiss, Brian J. ^{[3
]}

Ryan, Elizabeth P. ^{[2
]}

Henry, Charles S. ^{[1
]}

机构：

[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA

[2] Colorado State Univ, Dept Environm & Radiol Sci, Ft Collins, CO 80523 USA

[3] Colorado State Univ, Dept Microbiol Immunol & Pathol, Ft Collins, CO 80523 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2017年 / 56卷 / 24期

关键词：

antimicrobial resistance; nitrocefin; paper-based analytical devices; beta-lactam antibiotics; beta-lactamase; BETA-LACTAMASE; ANTIBIOTIC-RESISTANCE; ESCHERICHIA-COLI; SUSCEPTIBILITY; WATER; PREVALENCE; SECRETION; GENES;

D O I：

10.1002/anie.201702776

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Antimicrobial resistance (AMR), the ability of a bacterial species to resist the action of an antimicrobial drug, has been on the rise due to the widespread use of antimicrobial agents. Per the World Health Organization, AMR has an estimated annual cost of USD34 billion in the US and is predicted to be the number one cause of death worldwide by 2050. One way AMR bacteria can spread, and by which individuals can contract AMR infections, is through contaminated water. Monitoring AMR bacteria in the environment currently requires that samples be transported to a central laboratory for slow and labor intensive tests. We have developed an inexpensive assay using paper-based analytical devices (PADs) that can test for the presence of beta-lactamase-mediated resistance. To demonstrate viability, the PAD was used to detect beta-lactam resistance in wastewater and sewage and identified resistance in individual bacterial species isolated from environmental water sources.

引用

页码：6886 / 6890

页数：5

共 50 条

[21] Prevalence of and risk factors for antimicrobial-resistant fecal bacteria in beef cow-calf operations: A systematic review [J].

Ali, Ahmad ;

Denagamage, Thomas ;

Hernandez, Jorge A. ;

Lee, Alice C. Y. ;

Bittar, Joao H. J. ;

Jeong, Kwang C. ;

Kariyawasam, Subhashinie .

RESEARCH IN VETERINARY SCIENCE, 2025, 193

[22] Taxonomic diversity of antimicrobial-resistant bacteria and genes in the Red Sea coast [J].

Ullah, Riaz ;

Yasir, Muhammad ;

Bibi, Fehmida ;

Abujamel, Turki S. ;

Hashem, Anwar M. ;

Sohraba, Sayed Sartaj ;

Al-Ansari, Ahmed ;

Al-Sofyani, Abdulmohsin A. ;

Al-Ghamdi, Ahmed K. ;

Al-sieni, Abdulbasit ;

Azhar, Esam, I .

SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 677 :474-483

[23] Epidemiology and treatment of antimicrobial-resistant gram-negative bacteria in Korea [J].

Kim, Young Ah ;

Park, Yoon Soo .

KOREAN JOURNAL OF INTERNAL MEDICINE, 2018, 33 (02) :247-255

[24] Short communication: A countrywide survey of antimicrobial-resistant indicator bacteria in Kosovo's dairy farms [J].

Chandler, Jeffrey C. ;

Aljasir, Sulaiman F. ;

Hamidi, Afrim ;

Sylejmani, Driton ;

Gerow, Kenneth G. ;

Bisha, Bledar .

JOURNAL OF DAIRY SCIENCE, 2018, 101 (08) :6982-6989

[25] Effects of natural sunlight on antimicrobial-resistant bacteria (AMRB) and antimicrobial-susceptible bacteria (AMSB) in wastewater and river water [J].

Azuma, Takashi ;

Hayashi, Tetsuya .

SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 766

[26] Paper-based Analytical Devices [J].

Hideaki Hisamoto .

Analytical Sciences, 2017, 33 :753-753

[27] Ecological study on antimicrobial-resistant zoonotic bacteria transmitted by flies in cattle farms [J].

Mohammed, Asmaa N. ;

Abdel-Latef, Gihan K. ;

Abdel-Azeem, Naglaa M. ;

El-Dakhly, Khaled Mohamed .

PARASITOLOGY RESEARCH, 2016, 115 (10) :3889-3896

[28] Microplastics in marine pollution: Oceanic hitchhikers for the global dissemination of antimicrobial-resistant bacteria [J].

Queiroga, Gustavo ;

Vasquez-Ponce, Felipe ;

Martins-Goncalves, Thais ;

Lincopan, Nilton .

ONE HEALTH, 2025, 20

[29] Effects of Organic Soil Amendments on Antimicrobial-Resistant Bacteria in Urban Agriculture Environments [J].

Zeng, Qingyue ;

Lam, Kevin ;

Salcedo, Autumn ;

V. Tikekar, Rohan ;

Micallef, Shirley A. ;

Blaustein, Ryan A. .

JOURNAL OF FOOD PROTECTION, 2024, 87 (10)

[30] Are the Hands of Veterinary Staff a Reservoir for Antimicrobial-Resistant Bacteria? A Randomized Study to Evaluate Two Hand Hygiene Rubs in a Veterinary Hospital [J].

Espadale, Eva ;

Pinchbeck, Gina ;

Williams, Nicola J. ;

Timofte, Dorina ;

McIntyre, K. Marie ;

Schmidt, Vanessa M. .

MICROBIAL DRUG RESISTANCE, 2018, 24 (10) :1607-1616

← 1 2 3 4 5 →