Phosphodiester bond cleavage mediated by a cyclic β-sheet peptide-based dinuclear zinc(II) complex

被引：48
|
作者：
Yamada, K
Takahashi, Y
Yamamura, H
Araki, S
Saito, K
Kawai, M
机构：
[1] Nagoya Inst Technol, Dept Appl Chem, Showa Ku, Nagoya, Aichi 4668555, Japan
[2] Japan Sci & Technol Corp, ERATO, Yokoyama Cytolog Project, Tsukuba, Ibaraki 3002635, Japan
来源：
CHEMICAL COMMUNICATIONS | 2000年 / 14期
关键词：
D O I：
10.1039/b003370g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A dinuclear Zn(II) complex of N-2 delta,N-2 delta,N-2'delta,N-2'delta-tetrakis(2-pyridylmethyl) derivative of cyclic peptide gramicidin S markedly accelerated the cleavage of the phosphodiester linkage of the RNA model substrate 2-hydroxypropyl p-nitrophenyl phosphate.
引用
收藏
页码：1315 / 1316
页数：2
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