NRAMP1 and TNF-α polymorphisms and susceptibility to tuberculosis in Thais

被引：53
作者：
Vejbaesya, Sasijit
Chierakul, Nitipatana
Luangtrakool, Panpimon
Sermduangprateep, Chutima
机构：
[1] Mahidol Univ, Fac Med, Siriraj Hosp, Dept Transfus Med, Bangkok 10700, Thailand
[2] Mahidol Univ, Fac Med, Siriraj Hosp, Dept Med, Bangkok 10700, Thailand
来源：
RESPIROLOGY | 2007年 / 12卷 / 02期
关键词：
natural resistance-associated macrophage protein gene 1; Thais; tuberculosis; tumour necrosis factor;
D O I：
10.1111/j.1440-1843.2006.01037.x
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Polymorphisms in the natural resistance-associated macrophage protein gene 1 (NRAMP1) and tumour necrosis factor (TNF)-alpha gene have been found to be associated with susceptibility to tuberculosis in different populations. However, the results are inconsistent. This study aimed to determine whether NRAMP1 and TNF-alpha variants are associated with tuberculosis in Thais. Polymorphisms of NRAMP1 at INT4, D543N and the 3' untranslated region, and of TNF-alpha at +488, -238, and -308, were examined in 149 tuberculosis patients and 147 healthy controls. PCR using sequence-specific oligonucleotides and sequence-specific priming were used to genotype the NRAMP1 and TNF polymorphisms, respectively. There were no significant differences in the distribution of the genotype frequencies for the NRAMP1 and TNF-alpha polymorphisms between the patients and controls. The NRAMP1 and TNF-alpha genes are not associated with susceptibility to tuberculosis in Thais.
引用
收藏
页码：202 / 206
页数：5
相关论文
共 50 条
[31]   Sequence Variability in the NRAMP1 Gene among Indigenous and Exotic Chicken Types [J].
Desmond, Abazuh Uchenna ;
Olajide, Adekoya Khalid ;
Olufunmilayo, Oboh Bola .
MAKARA JOURNAL OF SCIENCE, 2019, 23 (02) :103-108
[32]   TNF-α antagonist treatment associated with tuberculosis [J].
Reactions Weekly, 2004, 1006 (1) :3-3
[33]   Reduced in vitro functional activity of human NRAMP1 (SLC11A1) allele that predisposes to increased risk of pediatric tuberculosis disease [J].
Gallant, C. J. ;
Malik, S. ;
Jabado, N. ;
Cellier, M. ;
Simkin, L. ;
Finlay, B. B. ;
Graviss, E. A. ;
Gros, P. ;
Musser, J. M. ;
Schurr, E. .
GENES AND IMMUNITY, 2007, 8 (08) :691-698
[34]   Correlation of Polymorphisms of Natural Resistance-Associated Macrophage Protein 1 (NRAMP1) Gene and Smoking with the Risk of Rheumatoid Arthritis in Chinese Han People [J].
Zou, Qinghua ;
Zhao, Yi ;
Wang, Yong ;
Fang, Yongfei ;
Liu, Yi .
MEDICAL SCIENCE MONITOR, 2019, 25 :5321-5326
[35]   Association between SLC11A1 (formerly NRAMP1) and the risk of sarcoidosis in Poland [J].
Anna Dubaniewicz ;
Sarra E Jamieson ;
M Dubaniewicz-Wybieralska ;
Michaela Fakiola ;
E Nancy Miller ;
Jenefer M Blackwell .
European Journal of Human Genetics, 2005, 13 :829-834
[36]   Association between SLC11A1 (formerly NRAMP1) and the risk of sarcoidosis in Poland [J].
Dubaniewicz, A ;
Jamieson, SE ;
Dubaniewicz-Wybieralska, MD ;
Fakiola, M ;
Miller, EN ;
Blackwell, JM .
EUROPEAN JOURNAL OF HUMAN GENETICS, 2005, 13 (07) :829-834
[37]   A genetic variant in the TRAF1/C5 gene lead susceptibility to active pulmonary tuberculosis by decreased TNF-α levels [J].
de Lima, Dhemerson Souza ;
de Brito, Carolina Fadoul ;
Barbosa, Aguyda Rayany Cavalcante ;
Figueira, Mariana Brasil de Andrade ;
Bonet, Julio Ceaser Maciel ;
Walzer, Joseph ;
Ramasawmy, Rajendranath ;
Ogusku, Mauricio Morishi ;
Sadahiro, Aya ;
Boechat, Antonio Luiz .
MICROBIAL PATHOGENESIS, 2021, 159
[38]   NRAMP1 is not associated with asthma, atopy, and serum immunoglobulin E levels in the French Canadian population [J].
A H Poon ;
C Laprise ;
M Lemire ;
T J Hudson ;
E Schurr .
Genes & Immunity, 2005, 6 :519-527
[39]   Association of Fcγ receptor IIb and IIIb polymorphisms with susceptibility to systemic lupus erythematosus in Thais [J].
Siriboonrit, U ;
Tsuchiya, N ;
Sirikong, M ;
Kyogoku, C ;
Bejrachandra, S ;
Suthipinittharm, P ;
Luangtrakool, K ;
Srinak, D ;
Thongpradit, R ;
Fujiwara, K ;
Chandanayingyong, D ;
Tokunaga, K .
TISSUE ANTIGENS, 2003, 61 (05) :374-383
[40]   Characterization of chicken natural resistance-associated macrophage protein encoding genes (Nramp1 and Nramp2) and association with salmonellosis resistance [J].
He, X. M. ;
Fang, M. X. ;
Zhang, Z. T. ;
Hu, Y. S. ;
Jia, X. Z. ;
He, D. L. ;
Liang, S. D. ;
Nie, Q. H. ;
Zhang, X. Q. .
GENETICS AND MOLECULAR RESEARCH, 2013, 12 (01) :618-630
12345