Synthesis of nitrogen-doped carbon nanocages for sensitive electrochemical detection of uric acid

被引：12

作者：

Han, Ruiyu ^{[1
]}

Ma, Jing ^{[1
]}

Yang, Chaoju ^{[2
]}

Cui, Tong ^{[3
]}

Liu, Wenjiao ^{[3
]}

Wang, Shusong ^{[1
]}

机构：

[1] Hebei Res Inst Family Planning, Hebei Key Lab Reprod Med, NHC Key Lab Family Planning & Hlth, Shijiazhuang 050051, Hebei, Peoples R China

[2] Hebei Gen Hosp, Clin Lab, Shijiazhuang 050051, Hebei, Peoples R China

[3] Hebei Noma Univ, Sch Chem & Mat Sci, Shijiazhuang 050024, Hebei, Peoples R China

来源：

MATERIALS LETTERS | 2019年 / 255卷

基金：

中国国家自然科学基金;

关键词：

Synthesis; Carbon materials; Uric acid; Electrochemical detection; Sensors; NANOPARTICLES; DOPAMINE; NANOTUBE; REDUCTION;

D O I：

10.1016/j.matlet.2019.126520

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

In this work, nitrogen-doped carbon nanocages were prepared for uric acid detection, which exhibits three dimensional hollow nanostructures with large specific surface area of 565 m(2) g(-1) and unique heteroatomic property. The as-synthesized nitrogen-doped carbon nanocages show high selectivity and sensitivity for uric acid detection accompanied with excellent stability. The developed electrochemical analysis for facile determination of uric acid shown a wide linear range of 0-1.0 mM, with the detection limit of 2.07 x 10(-2) mu M (S/N = 3). Moreover, this strategy was successfully used for uric acid detection in human serum and urine samples and demonstrated satisfied recoveries. The result in the present work suggests that nitrogen-doped carbon nanocages hold great potential to use as superior electrochemical sensors for uric acid determination. (C) 2019 Elsevier B.V. All rights reserved.

引用

页数：4

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