Metabolites from Marine Microorganisms, Micro, and Macroalgae: Immense Scope for Pharmacology

被引:110
作者
Barzkar, Noora [1 ]
Jahromi, Saeid Tamadoni [2 ]
Poorsaheli, Hadi Bolooki [3 ,4 ]
Vianello, Fabio [5 ]
机构
[1] Univ Hormozgan, Fac Marine Sci & Technol, Dept Marine Biol, Bandar Abbas 74576, Iran
[2] AREEO, Iranian Fisheries Sci Res Inst, Persian Gulf & Oman Sea Ecol Res Ctr, Bandar Abbas 93165, Iran
[3] Rd Housing & Urban Dev Res Ctr BHRC, Persian Gulf Branch, Bandar Abbas 93144, Iran
[4] Islamic Azad Univ, Dept Engn, Bandar Abbas 1696, Iran
[5] Univ Padua, Dept Comparat Biomed & Food Sci, Viale Univ 16, I-35020 Legnaro, Italy
关键词
marine microorganisms; natural products; pharmaceutical potential; bacteria; microalgae; macroalgae; GREEN-ALGA; NATURAL-PRODUCTS; SULFATED POLYSACCHARIDES; IN-VITRO; UNDARIA-PINNATIFIDA; BROWN ALGA; RED ALGAE; ANTIINFLAMMATORY ACTIVITIES; ANTIBACTERIAL ACTIVITY; ANTICOAGULANT ACTIVITY;
D O I
10.3390/md17080464
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Marine organisms produce a large array of natural products with relevance in drug discovery. These compounds have biological activities such as antioxidant, antibacterial, antitumor, antivirus, anticoagulant, anti-inflammatory, antihypertensive, antidiabetic, and so forth. Consequently, several of the metabolites have made it to the advanced stages of clinical trials, and a few of them are commercially available. In this review, novel information on natural products isolated from marine microorganisms, microalgae, and macroalgae are presented. Given due research impetus, these marine metabolites might emerge as a new wave of promising drugs.
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页数:29
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