Gut microbiota: Implications in Parkinson's disease

被引：170
作者：
Parashar, Arun [1 ]
Udayabanu, Malairaman [1 ]
机构：
[1] Jaypee Univ Informat Technol, PO Waknaghat, Waknaghat 173234, Himachal Prades, India
来源：
PARKINSONISM & RELATED DISORDERS | 2017年 / 38卷
关键词：
Gut microbiota; Parkinson's disease; Probiotics; Germ-free; Antibiotics; Fecal transplant; INTESTINAL BACTERIAL OVERGROWTH; L-DOPA ABSORPTION; ALPHA-SYNUCLEIN; DIETARY-INTAKE; VITAMIN-E; HELICOBACTER; MODEL; BRAIN; RISK; INFLAMMATION;
D O I：
10.1016/j.parkreldis.2017.02.002
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Gut microbiota (GM) can influence various neurological outcomes, like cognition, learning, and memory. Commensal GM modulates brain development and behavior and has been implicated in several neurological disorders like Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, anxiety, stress and much more. A recent study has shown that Parkinson's disease patients suffer from GM dysbiosis, but whether it is a cause or an effect is yet to be understood. In this review, we try to connect the dots between GM and PD pathology using direct and indirect evidence. (C) 2017 Elsevier Ltd. All rights reserved.
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页码：1 / 7
页数：7
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