Novel methods to optimize the effects of transcranial direct current stimulation: a systematic review of transcranial direct current stimulation patents

被引：9
作者：
Malavera, Alejandra [1 ]
Vasquez, Alejandra [1 ]
Fregni, Felipe [1 ]
机构：
[1] Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Spaulding Neuromodulat Ctr, Boston, MA USA
来源：
EXPERT REVIEW OF MEDICAL DEVICES | 2015年 / 12卷 / 06期
关键词：
high-definition transcranial direct current stimulation; optimization; patent; safety; systematic review; transcranial direct current stimulation; MAJOR DEPRESSION; TDCS; MODULATION; PAIN;
D O I：
10.1586/17434440.2015.1090308
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that has been extensively studied. While there have been initial positive results in some clinical trials, there is still variability in tDCS results. The aim of this article is to review and discuss patents assessing novel methods to optimize the use of tDCS. A systematic review was performed using Google patents database with tDCS as the main technique, with patents filling date between 2010 and 2015. Twenty-two patents met our inclusion criteria. These patents attempt to address current tDCS limitations. Only a few of them have been investigated in clinical trials (i.e., high-definition tDCS), and indeed most of them have not been tested before in human trials. Further clinical testing is required to assess which patents are more likely to optimize the effects of tDCS. We discuss the potential optimization of tDCS based on these patents and the current experience with standard tDCS.
引用
收藏
页码：679 / 688
页数：10
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