Dispermy - origin of diandric triploidy

被引:27
作者
McFadden, DE [1 ]
Jiang, R
Langlois, S
Robinson, WP
机构
[1] Childrens & Womens Hosp BC, Dept Pathol, Vancouver, BC V6H 3V4, Canada
[2] Childrens & Womens Hosp BC, Dept Med Genet, Vancouver, BC V6H 3V4, Canada
[3] Univ British Columbia, Vancouver, BC V6H 3V4, Canada
关键词
diandry; dispermy; triploidy;
D O I
10.1093/humrep/17.12.3037
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Triploidy may arise from either digynic or diandric fertilizations. Errors in the second meiotic division account for most digynic triploidy while most studies have found that similar to2/3 of diandric triploids arise as the result of dispermy and 1/3 as the result of meiotic errors giving rise to diploid sperm. Using molecular markers very close to the centromere, all 14 cases of diandric triploidy were shown to be the result of dispermy with no evidence to support a meiotic error as the origin of diandric triploids.
引用
收藏
页码:3037 / 3038
页数:2
相关论文
共 8 条
[1]   Parental origin and mechanisms of formation of triploidy: a study of 25 cases [J].
Baumer, A ;
Balmer, D ;
Binkert, F ;
Schinzel, A .
EUROPEAN JOURNAL OF HUMAN GENETICS, 2000, 8 (12) :911-917
[2]   ORIGIN OF HUMAN TRIPLOIDS [J].
JACOBS, PA ;
ANGELL, RR ;
BUCHANAN, IM ;
HASSOLD, TJ ;
MATSUYAMA, AM ;
MANUEL, B .
ANNALS OF HUMAN GENETICS, 1978, 42 (JUL) :49-57
[3]   Parental and meiotic origin of triploidy in the embryonic and fetal periods [J].
McFadden, DE ;
Langlois, S .
CLINICAL GENETICS, 2000, 58 (03) :192-200
[4]   PARENTAL ORIGIN OF TRIPLOIDY IN HUMAN FETUSES - EVIDENCE FOR GENOMIC IMPRINTING [J].
MCFADDEN, DE ;
KWONG, LC ;
YAM, IYL ;
LANGLOIS, S .
HUMAN GENETICS, 1993, 92 (05) :465-469
[5]   PARENTAL ORIGIN OF THE EXTRA HAPLOID CHROMOSOME SET IN TRIPLOIDIES DIAGNOSED PRENATALLY [J].
MINY, P ;
KOPPERS, B ;
DWORNICZAK, B ;
BOGDANOVA, N ;
HOLZGREVE, W ;
TERCANLI, S ;
BASARAN, S ;
REHDER, H ;
EXELER, R ;
HORST, J .
AMERICAN JOURNAL OF MEDICAL GENETICS, 1995, 57 (01) :102-106
[6]   Prevalence of the partial molar phenotype in triploidy of maternal and paternal origin [J].
Redline, RW ;
Hassold, T ;
Zaragoza, MV .
HUMAN PATHOLOGY, 1998, 29 (05) :505-511
[7]   Spontaneous frequencies of aneuploid and diploid sperm in 10 normal Chinese men: assessed by multicolor fluorescence in situ hybridization [J].
Shi, Q ;
Martin, RH .
CYTOGENETICS AND CELL GENETICS, 2000, 90 (1-2) :79-83
[8]   Parental origin and phenotype of triploidy in spontaneous abortions: Predominance of diandry and association with the partial hydatidiform mole [J].
Zaragoza, MV ;
Surti, T ;
Redline, RW ;
Millie, E ;
Chakravarti, A ;
Hassold, TJ .
AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 66 (06) :1807-1820