Do Non-steroidal Anti-inflammatory Drugs Cause Exacerbations of Inflammatory Bowel Disease?

被引:28
作者
Feagins, Linda A. [1 ,2 ,3 ]
Cryer, Byron L. [1 ,2 ,3 ]
机构
[1] VA N Texas Hlth Care Syst, Div Gastroenterol 111B1, Dallas, TX 75216 USA
[2] VA N Texas Hlth Care Syst, Div Hepatol, Dallas, TX 75216 USA
[3] Univ Texas SW Med Ctr Dallas, Dallas, TX 75216 USA
关键词
Non-steroidal anti-inflammatory drugs; Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; SELECTIVE CYCLOOXYGENASE-2 INHIBITORS; OPEN-LABEL TRIAL; ULCERATIVE-COLITIS; GASTROINTESTINAL-TRACT; RELAPSE; EICOSANOIDS; ROFECOXIB; REMISSION; INGESTION; CELECOXIB;
D O I
10.1007/s10620-009-1042-7
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The safety of non-steroidal anti-inflammatory drugs ( NSAIDs) in patients with inflammatory bowel disease (IBD) remains unclear. This report discusses potential mechanisms whereby NSAIDs might exacerbate IBD and reviews the available clinical data on the role of NSAIDs in causing exacerbations of ulcerative colitis (UC) and Crohn's disease ( CD).
引用
收藏
页码:226 / 232
页数:7
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