Diagnostic value of FDG PET/CT imaging in patients with surgically managed infective endocarditis: results of a retrospective analysis at a tertiary center

被引：10

作者：

Sag, Sabine Julia Maria ^{[1
]}

Menhart, Karin ^{[2
]}

Grosse, Jirka ^{[2
]}

Hitzenbichler, Florian ^{[3
]}

Hanses, Frank ^{[3
]}

Mohr, Arno ^{[3
]}

Salzberger, Bernd ^{[3
]}

Zerdzitzki, Matthaus ^{[4
]}

Hilker, Michael ^{[4
]}

Rupprecht, Leopold ^{[4
]}

Hellwig, Dirk ^{[2
]}

Schmid, Christof ^{[4
]}

Maier, Lars Siegfried ^{[1
]}

Sag, Can Martin ^{[1
]}

机构：

[1] Univ Hosp Regensburg, Dept Internal Med 2, Franz Josef Str Allee 11, D-93053 Regensburg, Germany

[2] Univ Hosp Regensburg, Dept Nucl Med, Regensburg, Germany

[3] Univ Hosp Regensburg, Dept Infect Prevent & Infect Dis, Regensburg, Germany

[4] Univ Hosp Regensburg, Dept Cardiothorac Surg, Regensburg, Germany

来源：

JOURNAL OF NUCLEAR CARDIOLOGY | 2022年 / 29卷 / 03期

关键词：

Inflammation; PET; image interpretation; EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY;

D O I：

10.1007/s12350-020-02457-x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background We assessed the diagnostic value of FDG PET/CT in a real-world cohort of patients with surgically managed infective endocarditis (IE). Methods We performed a retrospective analysis of all patients hospitalized in a tertiary IE referral medical center from January 2014 to October 2018 fulfilling the following criteria: ICD-10 code for IE and OPS code for both, heart surgery and FDG PET/CT. Results Final analysis included 29 patients, whereof 28 patients had surgically proven IE. FDG PET/CT scan was true-positive in 15 patients (sensitivity (SEN) 56%) and false-negative in 12 patients. Combination of Duke criteria (DC) with FDG PET/CT scan resulted in gain of SEN for all patients with confirmed IE (SEN of DC 79% vs SEN of combination DC and FDG PET/CT 89%), driven by a relevant gain in PVE patients only (SEN of DC 78% vs SEN of combination DC and FDG PET/CT 94%). Interestingly, higher prosthesis age was observed in patients with false-negative scans. Conclusions We found a SEN of 56% for FDG PET/CT in a real-world cohort of patients with surgically proven IE which was associated with a 16% gain of IE diagnosis in patients with PVE when combined with DC.

引用

页码：1191 / 1204

页数：14

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