Microwave-assisted Synthesis of Pyrazolo[4,3-f]quinolin-7-one Derivatives via Multi-component Reactions

被引：8

作者：

Peng Juhua ^{[2
]}

Hao Wenjuan ^{[1
]}

Wang Xiang ^{[1
]}

Tu Shujiang ^{[1
]}

Ma Ning ^{[1
]}

Zhang Ge ^{[1
]}

机构：

[1] Xuzhou Normal Univ, Coll Chem & Chem Engn, Xuzhou 221116, Jiangsu, Peoples R China

[2] Lianyungang Teachers Coll, Lianyungang 222006, Jiangsu, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2009年 / 27卷 / 09期

基金：

中国国家自然科学基金;

关键词：

pyrazolo[4,3-f]quinolin-7-one; microwave irradiation; multi-component reaction; SUBSTITUTED 2,5-DIOXO-1,2,3,4,5,6,7,8-OCTAHYDROQUINOLINES; QUINOLINE DERIVATIVES; INHIBITORS; SOLVENT; 5-LIPOXYGENASE; IRRADIATION; CHEMISTRY; WATER;

D O I：

10.1002/cjoc.200990287

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of new pyrazolo[4,3-f]quinolin-7-one derivatives were synthesized by multi-component reactions of equimolar amount of aromatic aldehydes with 2,2-dimethyl-1,3-dioxane-4,6-dione and 1H-indazol-5-amine in ethylene glycol without catalyst under microwave irradiation. This one-pot protocol has the advantage of good yields, simple workup procedure and shorter reaction time.

引用

页码：1707 / 1710

页数：4

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