ATMOSPHERIC PRESSURE ION SOURCES

被引：194
作者：
Covey, Thomas R. [1 ]
Thomson, Bruce A. [1 ]
Schneider, Bradley B. [1 ]
机构：
[1] SCIEX Ltd, MDS Analyt Technol, 71 4 Valley Dr, Concord, ON L4K 4V8, Canada
来源：
MASS SPECTROMETRY REVIEWS | 2009年 / 28卷 / 06期
关键词：
atmospheric pressure ion source; atmospheric pressure chemical ionization; electrospray; ion transport; ion guides; ion focusing; liquid chromatography; mass spectrometty; IONIZATION-MASS-SPECTROMETRY; PERFORMANCE LIQUID-CHROMATOGRAPHY; SHEATHLESS ELECTROSPRAY EMITTERS; FUSED-SILICA CAPILLARIES; SONIC SPRAY IONIZATION; INTERFACE REGION FLOWS; NANO-ELECTROSPRAY; ASSISTED ELECTROSPRAY; HIGH-VOLTAGE; GAS-PHASE;
D O I：
10.1002/mas.20246
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
This review of atmospheric pressure ion sources discusses major developments that have occurred since 1991. Advances in the instrumentation and understanding of the key physical principles are the primary focus. Developments with electrospray and atmospheric pressure chemical ionization and variations encompassing adaptations for surface analysis, ambient air analysis, high throughput, and modification of the ionization mechanism art, covered. An important and limiting consequence of atmospheric pressure chemical ionization, chemical noise, is discussed as is techniques being employed to ameliorate the problem. Ion transfer and transport from atmospheric pressure into deep vacuum is an area undergoing constant improvement and refinement so is given considerable consideration in this review. (C) 2009 Wiley Periodicals, Inc., Mass Spec Rev 28:870-897, 2009
引用
收藏
页码：870 / 897
页数：28
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