Targeting estrogen receptor mutations for treatment of endocrine therapy resistance in breast cancer

被引：0
|
作者：
Alluri, P. G. [1 ]
Larios, J. M. [1 ]
Malik, R. [1 ]
Hayes, D. F. [1 ]
Speers, C. W. [1 ]
Rae, J. M. [1 ]
Chinnaiyan, A. M. [1 ]
机构：
[1] Univ Michigan, Sch Med, Ann Arbor, MI USA
来源：
CANCER RESEARCH | 2017年 / 77卷
关键词：
D O I：
10.1158/1538-7445.SABCS16-P6-12-05
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P6-12-05
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Kinase fusions drive endocrine resistance in estrogen receptor-positive breast cancer
    Liu, Bo
    Ross, Dara S.
    Schram, Alison M.
    Razavi, Pedram
    Lagana, Stephen M.
    Zhang, Yanming
    Scaltriti, Maurizio
    Bromberg, Jacqueline F.
    Ladanyi, Marc
    Hyman, David M.
    Drilon, Alexander
    Zahir, Ahmet
    Benayed, Ryma
    Hechtman, Jaclyn F.
    Chandarlapaty, Sarat
    CANCER RESEARCH, 2020, 80 (16)
  • [42] Estrogen Receptor Pathway Activity Score to Predict Clinical Response or Resistance to Neoadjuvant Endocrine Therapy in Primary Breast Cancer
    Inda, Marcia A.
    Blok, Erik J.
    Kuppen, Peter J. K.
    Charehbili, Ayoub
    den Biezen-Timmermans, Eveline C.
    van Brussel, Anne
    Fruytier, Sevgi E.
    Kranenbarg, Elma Meershoek-Klein
    Kloet, Susan
    van der Burg, Bart
    Martens, John W. M.
    Sims, Andrew H.
    Turnbull, Arran K.
    Dixon, J. Michael
    Verhaegh, Wim
    Kroep, Judith R.
    van de Velde, Cornelis J. H.
    van de Stolpe, Anja
    MOLECULAR CANCER THERAPEUTICS, 2020, 19 (02) : 680 - 689
  • [43] Characterizing hormone therapy-resistance phenotypes in metastatic breast cancer conferred by estrogen receptor (ER) mutations
    Jia, Shanhang
    Hessenius, Ryan
    Ngo, Marilyn
    Wang, Peilu
    Bahreini, Amir
    Chen, Ning
    Ding, Zhijie
    Shun, Tong Ying
    Taylor, Lansing
    Puhalla, Shannon
    Lee, Adrian
    Oesterreich, Steffi
    Stern, Andrew M.
    CANCER RESEARCH, 2017, 77
  • [44] Endocrine-targeting therapies shift the breast microbiome to reduce estrogen receptor-a breast cancer risk
    Arnone, Alana A.
    Tsai, Yu-Ting
    Cline, J. Mark
    Wilson, Adam S.
    Westwood, Brian
    Seger, Meghan E.
    Chiba, Akiko
    Howard-McNatt, Marissa
    Levine, Edward A.
    Thomas, Alexandra
    Soto-Pantoja, David R.
    Cook, Katherine L.
    CELL REPORTS MEDICINE, 2025, 6 (01)
  • [45] Oral Selective Estrogen Receptor Downregulators (SERDs), a Breakthrough Endocrine Therapy for Breast Cancer
    McDonnell, Donald P.
    Wardell, Suzanne E.
    Norris, John D.
    JOURNAL OF MEDICINAL CHEMISTRY, 2015, 58 (12) : 4883 - 4887
  • [46] Loss of estrogen receptor in recurrent breast cancer is associated with poor response to endocrine therapy
    Kuukasjarvi, T
    Kononen, J
    Helin, H
    Holli, K
    Isola, J
    JOURNAL OF CLINICAL ONCOLOGY, 1996, 14 (09) : 2584 - 2589
  • [47] Oral SERD, a Novel Endocrine Therapy for Estrogen Receptor-Positive Breast Cancer
    Neupane, Niraj
    Bawek, Sawyer
    Gurusinghe, Sayuri
    Ghaffary, Elham Moases
    Mirmosayyeb, Omid
    Thapa, Sangharsha
    Falkson, Carla
    O'Regan, Ruth
    Dhakal, Ajay
    CANCERS, 2024, 16 (03)
  • [48] ESR1 Mutations Are Not a Common Mechanism of Endocrine Resistance in Patients With Estrogen Receptor-Positive Breast Cancer Treated With Neoadjuvant Aromatase Inhibitor Therapy
    Reinert, Tomas
    Ramalho, Susana
    Antunes de Vasconcelos, Vivian Castro
    Silva, Leonardo Roberto
    Ribeiro da Silva, Ana Elisa
    de Andrade, Camila Annicchino
    de Paula Leite Kraft, Maria Beatriz
    Coelho, Guilherme Portela
    Mandelli, Jovana
    Binotto, Monique
    Cabello, Cesar
    de Paiva Silva, Geisilene Russano
    Bines, Jose
    Barrios, Carlos H.
    Ellis, Matthew J.
    Graudenz, Marcia Silveira
    FRONTIERS IN ONCOLOGY, 2020, 10
  • [49] Estrogen receptor downregulators: New options in endocrine therapy for advanced breast cancer - Introduction
    O'Shaughnessy, J
    Bhardwaj, S
    CLINICAL THERAPEUTICS, 2002, 24 : A1 - A2
  • [50] Role of mitochondria and glutamine metabolism in therapy resistance: Combined targeting of estrogen receptor alpha and exportin 1 in endocrine resistant breast cancers
    Cotul, Eylem Kulkoyluoglu
    Smith, Brandi Patrice
    Chang, Hua
    Landesman, Yosef
    Duong, Kevin
    Erdogan, Zeynep Madak
    CANCER RESEARCH, 2019, 79 (13)
12345