A Rare Presentation of Biclonal Gammopathy in Multiple Myeloma with Simultaneous Extramedullary Involvement: A Case Report

被引：4

作者：

Kancharla, Pragnan ^{[1
]}

Patel, Eshan ^{[1
]}

Hennrick, Kenneth ^{[1
]}

Ibrahim, Sherif ^{[2
]}

Goldfinger, Mendel ^{[1
]}

机构：

[1] New York Presbyterian Brooklyn Methodist Hosp, Brooklyn, NY USA

[2] West Plains Hosp, White Plains, NY USA

来源：

CASE REPORTS IN ONCOLOGY | 2019年 / 12卷 / 02期

关键词：

Biclonal gammopathy; Extra medullary myeloma; Multiple myeloma; MONOCLONAL IGG; BANDS;

D O I：

10.1159/000499902

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Multiple myeloma is characterized by an abnormal clone of plasma cell infiltration in the bone marrow and presence of a high level monoclonal immunoglobulin (M-protein) in the serum or urine in most cases. The monoclonal protein is usually detected as a discrete band in the gamma globulin region by serum protein electrophoresis. Rarely, it may show a simultaneous presence of two distinct bands, which could be either from a single clone, or two separate clones. We report a very unusual presentation of biclonality with lambda restricted IgG predominant cells from cervical lymph node and kappa restricted IgA cells from the bone marrow simultaneously. (C) 2019 The Author(s) Published by S. Karger AG, Basel

引用

页码：537 / 542

页数：6

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