SURVEY OF STEREOTACTIC BODY RADIATION THERAPY IN JAPAN BY THE JAPAN 3-D CONFORMAL EXTERNAL BEAM RADIOTHERAPY GROUP

被引:111
作者
Nagata, Yasushi [1 ]
Hiraoka, Masahiro [2 ]
Mizowaki, Takashi [2 ]
Narita, Yuichiro [2 ]
Matsuo, Yukinori [2 ]
Norihisa, Yoshiki [2 ]
Onishi, Hiroshi [3 ]
Shirato, Hiroki [4 ]
机构
[1] Hiroshima Univ Hosp, Div Radiat Oncol, Hiroshima 7348551, Japan
[2] Kyoto Univ, Dept Radiat Oncol, Kyoto, Japan
[3] Yamanashi Univ, Dept Radiol, Yamanashi, Japan
[4] Hokkaido Univ, Dept Radiol, Sapporo, Hokkaido 060, Japan
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2009年 / 75卷 / 02期
关键词
CELL LUNG-CANCER; MEDICALLY INOPERABLE PATIENTS; PHASE-I/II TRIAL; CLINICAL-OUTCOMES; DOSE IRRADIATION; LIVER METASTASES; TUMORS; CARCINOMA; FRAME; SBRT;
D O I
10.1016/j.ijrobp.2009.02.087
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: To recognize the current status of stereotactic body radiotherapy (SBRT) in Japan, using a nationwide survey conducted by the Japan 3-D Conformal External Beam Radiotherapy Group. Methods and Materials: The questionnaire was sent by mail to 117 institutions. Ninety-four institutions (80%) responded by the end of November 2005. Fifty-three institutions indicated that they have already started SBRT, and 38 institutions had been reimbursed by insurance. Results: A total of 1111 patients with histologically confirmed lung cancer were treated. Among these patients, 637 had TIN0M0 and 272 had T2N0M0 lung cancer. Metastatic lung cancer was found in 702 and histologically unconfirmed lung tumor in 291 patients. Primary liver cancer was found in 207 and metastatic liver cancer in 76 patients. The most frequent schedule used for primary lung cancer was 48Gy in 4 fractions at 22 institutions (52%), followed by 50Gy in 5 fractions at I I institutions (26%) and 60Gy in 8 fractions at 4 institutions (10%). The tendency was the same for metastatic lung cancer. The average number of personnel involved in SBRT was 1.8 radiation oncologists, including 1.1 certified radiation oncologists, 2.8 technologists, 0.7 nurses, and 0.6 certified quality assurance personnel and 0.3 physicists. The most frequent amount of time for treatment planning was 61-120min, for quality assurance was 50-60min, and for treatment was 30min. There were 14 (0.6% of all cases) reported Grade 5 complications: 11 cases of radiation pneumonitis, 2 cases of hemoptysis, and 1 case of radiation esophagitis. Conclusion: The current status of SBRT in Japan was surveyed. (C) 2009 Elsevier Inc.
引用
收藏
页码:343 / 347
页数:5
相关论文
共 31 条
[1]   Factors important for efficacy of stereotactic body radiotherapy of medically inoperable stage I lung cancer. A retrospective analysis of patients treated in the Nordic countries [J].
Baumann, Pia ;
Nyman, Jan ;
Lax, Ingmar ;
Friesland, Signe ;
Hoyer, Morten ;
Ericsson, Suzanne Rehn ;
Johansson, Karl-Axel ;
Ekberg, Lars ;
Morhed, Elisabeth ;
Paludan, Merete ;
Wittgren, Lena ;
Blomgren, Henrik ;
Lewensohn, Rolf .
ACTA ONCOLOGICA, 2006, 45 (07) :787-795
[2]   STEREOTAXIC HIGH-DOSE FRACTION RADIATION-THERAPY OF EXTRACRANIAL TUMORS USING AN ACCELERATOR - CLINICAL-EXPERIENCE OF THE FIRST 31 PATIENTS [J].
BLOMGREN, H ;
LAX, I ;
NASLUND, I ;
SVANSTROM, R .
ACTA ONCOLOGICA, 1995, 34 (06) :861-870
[3]  
Blomgren H., 1998, J RADIOSURGERY, V1, P63, DOI [10.1023/B:JORA.0000010880.40483.c4, DOI 10.1023/B:JORA.0000010880.40483.C4]
[4]   Individualized image guided iso-NTCP based liver cancer SBRT [J].
Dawson, Laura A. ;
Eccles, Cynthia ;
Craig, Tim .
ACTA ONCOLOGICA, 2006, 45 (07) :856-864
[5]   Stereotactic, single-dose irradiation of stage I non-small cell lung cancer and lung metastases [J].
Fritz, Peter ;
Kraus, Hans-Joerg ;
Muehlnickel, Werner ;
Hammer, Udo ;
Doelken, Wolfram ;
Engel-Riedel, Walburga ;
Chemaissani, Assad ;
Stoelben, Erich .
RADIATION ONCOLOGY, 2006, 1 (1)
[6]   Clinical outcomes of single-fraction stereotactic radiation therapy of lung tumors [J].
Hara, R ;
Itami, J ;
Kondo, T ;
Aruga, T ;
Uno, T ;
Sasano, N ;
Ohnishi, K ;
Kiyozuka, M ;
Fuse, M ;
Ito, M ;
Naoi, K ;
Kohno, Y .
CANCER, 2006, 106 (06) :1347-1352
[7]   Stereotactic single-dose radiation therapy of liver tumors:: Results of a phase I/II trial [J].
Herfarth, KK ;
Debus, J ;
Lohr, F ;
Bahner, ML ;
Rhein, B ;
Fritz, P ;
Höss, A ;
Schlegel, W ;
Wannenmacher, MF .
JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (01) :164-170
[8]   Extracranial radiosurgery (stereotactic body radiation therapy) for oligometastases [J].
Kavanagh, BD ;
McGarry, RC ;
Timmerman, RD .
SEMINARS IN RADIATION ONCOLOGY, 2006, 16 (02) :77-84
[9]   Interim analysis of a prospective phase I/II trial of SBRT for liver metastases [J].
Kavanagh, Brian D. ;
Schefter, Tracey E. ;
Cardenes, Higinia R. ;
Stieber, Volker W. ;
Raben, David ;
Timmerman, Robert D. ;
McCarter, Martin D. ;
Burri, Stuart ;
Nedzi, Lucien A. ;
Sawyer, Timothy E. ;
Gaspar, Laurie E. .
ACTA ONCOLOGICA, 2006, 45 (07) :848-855
[10]   STEREOTAXIC RADIOTHERAPY OF MALIGNANCIES IN THE ABDOMEN - METHODOLOGICAL ASPECTS [J].
LAX, I ;
BLOMGREN, H ;
NASLUND, I ;
SVANSTROM, R .
ACTA ONCOLOGICA, 1994, 33 (06) :677-683