Pertussis in the Netherlands: An outbreak despite high levels of immunization with whole-cell vaccine

被引：114

作者：

deMelker, HE ^{[1
]}

ConynvanSpaendonck, MAE ^{[1
]}

Rumke, H ^{[1
]}

vanWijngaarden, JK ^{[1
]}

Mooi, FR ^{[1
]}

Schellekens, JFP ^{[1
]}

机构：

[1] INSPECTORATE HLTH,RIJSWIJK,NETHERLANDS

来源：

EMERGING INFECTIOUS DISEASES | 1997年 / 3卷 / 02期

关键词：

D O I：

10.3201/eid0302.970211

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 1996, a sudden increase in pertussis incidence was reported in the Netherlands (2.1 per 100,000 in 1995, 18 per 100,000 in 1996). Although not all potential surveillance artifacts could be excluded, it is highly probable that the data reflect a true outbreak. However, the cause of this increase has not yet been determined. Further research is directed to the severity of disease and a possible mismatch between the vaccine and the circulating Bordetella strains.

引用

页码：175 / 178

页数：4

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