Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex

被引:66
作者
Choi, Min Sun [1 ]
Yoon, Minji [1 ]
Baeg, Jin-Ook [2 ]
Kim, Jinheung [1 ]
机构
[1] Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 120750, South Korea
[2] Korea Res Inst Chem Technol, Adv Chem Technol Div, Taejon 305343, South Korea
关键词
BINDING; RUTHENIUM(II); FLUORESCENCE; QUADRUPLEXES; POLYMER; WATER;
D O I
10.1039/b915994k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A homogeneous assay is reported using Ru(phen)(2)(dppz)(2+) and a K+-binding aptamer for the selective and sensitive detection of a target oligonucleotide and potassium ions, based on reduction in fluorescence emission according to the formation of the G-quadruplex structure from the aptamer in the presence of K+.
引用
收藏
页码:7419 / 7421
页数:3
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