Trace element supplementation in parenteral nutrition: Pharmacy, posology, and monitoring guidance

被引:25
作者
Hardy, Gil [2 ]
Maria Menendez, Ana [3 ]
Manzanares, William [1 ]
机构
[1] Univ Republica, Sch Med, Dept Crit Care Med, Montevideo, Uruguay
[2] Massey Univ, Inst Food Nutr & Human Hlth, Auckland, New Zealand
[3] Inst Argentino Educ & Invest Nutr, Buenos Aires, DF, Argentina
关键词
Trace elements; Parenteral nutrition; CRITICALLY-ILL PATIENTS; ZINC SUPPLEMENTATION; CHROMIUM DEFICIENCY; COPPER DEFICIENCY; XANTHINE-OXIDASE; DOUBLE-BLIND; SELENIUM; IRON; CHILDREN; REQUIREMENTS;
D O I
10.1016/j.nut.2009.03.004
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
We review the general functions leading to interactions between micronutrients and other constituents that can affect their bioavailability in parenteral nutrition (PN) admixtures, assess micronutrient status of PN patients at risk of deficiencies or toxicities by laboratory testing, clinical signs, and symptoms, emphasize the importance of vigilance regarding potential chemical and physical incompatibilities in PN admixtures, and highlight the need for manufacturers and pharmacists to carefully monitor and minimize levels of trace element contamination in all PN products. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:1073 / 1084
页数:12
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