Chemoselective inhibition of the hydrogenolysis of the MPM protective group for phenolic hydroxy functions using a Pd/C-pyridine catalyst

被引：49

作者：

Sajiki, H ^{[1
]}

Kuno, H ^{[1
]}

Hirota, K ^{[1
]}

机构：

[1] GIFU PHARMACEUT UNIV,MED CHEM LAB,GIFU 502,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 03期

关键词：

D O I：

10.1016/S0040-4039(96)02309-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient method for the selective hydrogenation of phenolic benzyl ether, Cbz, benzyl ester, nitro and olefin functions distinguishing from the MPM (4-methoxybenzyl) protective group for the phenolic hydroxy groups was accomplished by the addition of pyridine to the Pd/C-catalyzed reduction system. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：399 / 402

页数：4

共 12 条

[1]

CZECH BP, 1984, J ORG CHEM, V49, P4077

[2]

DAVIS R, 1982, SYNTHESIS-STUTTGART, P987

[3]

FREIFELDER M, 1971, PRACTICAL CATALYTIC, P398

[4]

GREENE TW, 1991, PROTECTIVE GROUPS OR, P47