Galvanotactic Phenomenon Induced by Non-Contact Electrostatic Field: Investigation in a Scratch Assay

被引：0

作者：

Caramazza, Laura ^{[1
,2
]}

De Angelis, Annalisa ^{[1
,2
]}

Remondini, Daniel ^{[3
]}

Castellani, Gastone ^{[4
]}

Liberti, Micaela ^{[1
]}

Apollonio, Francesca ^{[1
]}

Zironi, Isabella ^{[3
]}

机构：

[1] Sapienza Univ Rome, Dept Informat Engn Elect & Telecommun, Rome, Italy

[2] Ist Italiano Tecnol, Ctr Life Nano Sci Sapienza, I-00161 Rome, Italy

[3] Univ Bologna, Phys & Astron Dept, I-40126 Bologna, Italy

[4] Univ Bologna, Dept Specialized Diagnost & Expt Med, I-40126 Bologna, Italy

来源：

42ND ANNUAL INTERNATIONAL CONFERENCES OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY: ENABLING INNOVATIVE TECHNOLOGIES FOR GLOBAL HEALTHCARE EMBC'20 | 2020年

关键词：

ELECTRIC-FIELDS; CELL-MIGRATION; STIMULATION;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Non-contact galvanotaxis as a way to drive the cells migration could be a promising tool for a variety of biomedical applications, such as wound healing control, avoiding the interaction between electrodes and cell cultures. To this regard, the efficacy of this electrical stimulus application has to be deeper studied to control physiological migratory phenomena in a remote way. Aim of this work is to provide an experimental investigation on the mobility of cells exposed to a static electric field in a "non-contact" mode, supported by a suitable modeling of the electric field distribution inside the experimental setup. In particular, scratch assays have been carried out placing the electrodes outside the cells medium support and changing the cells holder to study more than one configuration.

引用

页码：2520 / 2523

页数：4

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