Analysis of similarity/dissimilarity of DNA sequences based on nonoverlapping triplets of nucleotide bases

被引：71

作者：

Liao, B ^{[1
]}

Wang, TM ^{[1
]}

机构：

[1] Dalian Univ Technol, Dept Appl Math, Dalian 116024, Peoples R China

来源：

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES | 2004年 / 44卷 / 05期

关键词：

D O I：

10.1021/ci034271f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We consider a 6-D representation of triplets of nucleotide bases of DNA sequences. Based on this representation, we outline an approach by constructing a 3-component vector whose components are the normalized leading eigenvalues of the L/L matrices associated with the triplets derived from DNA sequences. The examination of similarities/dissimilarities among the coding sequences of the first exon of beta-globin gene of different species illustrates the utility of the approach.

引用

页码：1666 / 1670

页数：5

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