Platelet-Rich Plasma From Basic Science to Clinical Applications

被引：868
作者：
Foster, Timothy E. [1 ]
Puskas, Brian L. [1 ]
Mandelbaum, Bert R. [2 ]
Gerhardt, Michael B. [2 ]
Rodeo, Scott A. [3 ]
机构：
[1] Boston Univ, Sch Med, Boston, MA 02118 USA
[2] Santa Monica Orthopaed & Sports Med Grp, Santa Monica, CA USA
[3] Hosp Special Surg, New York, NY 10021 USA
来源：
AMERICAN JOURNAL OF SPORTS MEDICINE | 2009年 / 37卷 / 11期
关键词：
platelet-rich plasma (PRP); growth factors; AUTOLOGOUS PREPARATION RICH; MESENCHYMAL STEM-CELLS; GROWTH-FACTORS ENHANCE; FREEZE-DRIED BONE; TIBIAL OSTEOTOMY; GENE-EXPRESSION; MUSCLE INJURIES; TENDON REPAIR; BLOOD-LOSS; GEL;
D O I：
10.1177/0363546509349921
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Platelet-rich plasma (PRP) has been utilized in surgery for 2 decades; there has been a recent interest in the use of PRP for the treatment of sports-related injuries. PRP contains growth factors and bioactive proteins that influence the healing of tendon, ligament, muscle, and bone. This article examines the basic science of PRP, and it describes the current clinical applications in sports medicine. This study reviews and evaluates the human studies that have been published in the orthopaedic surgery and sports medicine literature. The use of PRP in amateur and professional sports is reviewed, and the regulation of PRP by antidoping agencies is discussed.
引用
收藏
页码：2259 / 2272
页数：14
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