RESPIRATORY VIRUS EPIDEMIOLOGY AMONG US INFANTS WITH SEVERE BRONCHIOLITIS: ANALYSIS OF 2 MULTICENTER, MULTIYEAR COHORT STUDIES

被引:18
|
作者
Hasegawa, Kohei [1 ]
Goto, Tadahim [1 ]
Hirayama, Atsushi [2 ]
Laham, Federico R. [3 ]
Mansbach, Jonathan M. [4 ]
Piedra, Pedro A. [5 ,6 ,7 ]
Camargo, Carlos A., Jr. [1 ]
机构
[1] Harvard Med Sch, Massachusetts Gen Hosp, Dept Emergency Med, Boston, MA 02115 USA
[2] Natl Cerebral & Cardiovasc Ctr, Suita, Osaka, Japan
[3] Arnold Palmer Hosp Children, Dept Infect Dis, Orlando, FL USA
[4] Harvard Med Sch, Dept Med, Boston Childrens Hosp, Boston, MA 02115 USA
[5] Baylor Coll Med, Dept Mol Virol, Houston, TX 77030 USA
[6] Baylor Coll Med, Dept Microbiol, Houston, TX 77030 USA
[7] Baylor Coll Med, Dept Pediat, Houston, TX 77030 USA
基金
美国国家卫生研究院;
关键词
respiratory syncytial virus; rhinovirus; bronchiolitis; children; epidemiology; UNITED-STATES; HOSPITALIZATIONS;
D O I
10.1097/INF.0000000000002279
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In 2 multicenter cohort studies of 2912 infants hospitalized for bronchiolitis during 2007-2014, the 5 most common pathogens were RSV (76.5%), rhinovirus (23.8%), coronavirus (6.9%), adenovirus (6.4%) and human metapneumovirus (6.0%). Hospitalization months significantly differed for these common pathogens (P <= 0.01), except for coronavirus (P = 0.30). There was a significant heterogeneity in temporal patterns by region in RSV-A and -B (both P < 0.001).
引用
收藏
页码:E180 / E183
页数:5
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