RESPIRATORY VIRUS EPIDEMIOLOGY AMONG US INFANTS WITH SEVERE BRONCHIOLITIS: ANALYSIS OF 2 MULTICENTER, MULTIYEAR COHORT STUDIES

被引：18

作者：

Hasegawa, Kohei ^{[1
]}

Goto, Tadahim ^{[1
]}

Hirayama, Atsushi ^{[2
]}

Laham, Federico R. ^{[3
]}

Mansbach, Jonathan M. ^{[4
]}

Piedra, Pedro A. ^{[5
,6
,7
]}

Camargo, Carlos A., Jr. ^{[1
]}

机构：

[1] Harvard Med Sch, Massachusetts Gen Hosp, Dept Emergency Med, Boston, MA 02115 USA

[2] Natl Cerebral & Cardiovasc Ctr, Suita, Osaka, Japan

[3] Arnold Palmer Hosp Children, Dept Infect Dis, Orlando, FL USA

[4] Harvard Med Sch, Dept Med, Boston Childrens Hosp, Boston, MA 02115 USA

[5] Baylor Coll Med, Dept Mol Virol, Houston, TX 77030 USA

[6] Baylor Coll Med, Dept Microbiol, Houston, TX 77030 USA

[7] Baylor Coll Med, Dept Pediat, Houston, TX 77030 USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2019年 / 38卷 / 08期

基金：

美国国家卫生研究院;

关键词：

respiratory syncytial virus; rhinovirus; bronchiolitis; children; epidemiology; UNITED-STATES; HOSPITALIZATIONS;

D O I：

10.1097/INF.0000000000002279

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 2 multicenter cohort studies of 2912 infants hospitalized for bronchiolitis during 2007-2014, the 5 most common pathogens were RSV (76.5%), rhinovirus (23.8%), coronavirus (6.9%), adenovirus (6.4%) and human metapneumovirus (6.0%). Hospitalization months significantly differed for these common pathogens (P <= 0.01), except for coronavirus (P = 0.30). There was a significant heterogeneity in temporal patterns by region in RSV-A and -B (both P < 0.001).

引用

页码：E180 / E183

页数：5

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