Dynamics of immune response to porine from Yersinia pseudotuberculosis outer membrane

被引:2
|
作者
Portnyagina, OY [1 ]
Novikova, OD [1 ]
Vostrikova, OP [1 ]
Solov'eva, TF [1 ]
机构
[1] Russian Acad Sci, Pacific Inst Bioorgan Chem, Far E Div, Vladivostok 690022, Russia
关键词
porins of outer membrane of gram-negative bacteria; immune response; dynamics of antibody level;
D O I
10.1007/BF02433200
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The dynamics of immune response to pore-forming protein isolated from the outer membrane of Yersinia pseudotuberculosis was studied on CBA and BALB/c mice. Experiments revealed a waveform curves of antibody levels to different porin forms reflecting the successions of immunoglobulin classes and superposition of independent responses to various antigen determinants. The dynamic of immune response to porin depends on the molecular form and dose of the antigen.
引用
收藏
页码:1035 / 1038
页数:4
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