Spatial heterogeneity in the heart: Recent insights and open questions

被引:19
作者
Decking, UKM [1 ]
机构
[1] Univ Dusseldorf, Inst Herz & Kreislaufphysiol, D-40001 Dusseldorf, Germany
[2] NHLBI, Cardiac Energet Lab, NIH, Bethesda, MD 20892 USA
来源
NEWS IN PHYSIOLOGICAL SCIENCES | 2002年 / 17卷
关键词
D O I
10.1152/nips.01393.2002
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Within the left ventricular myocardium and despite its rather homogeneous structure, local myocardial perfusion varies substantially. Areas of low and high local flow differ with regard to substrate uptake, energy turnover, and demand. This spatial heterogeneity is related to distinct differences in local protein expression, forming the basis of a novel homeostatic mechanism.
引用
收藏
页码:246 / 250
页数:5
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